MULTISPECIES: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA

LOCUS       WP_003113700             337 aa            linear   BCT 01-APR-2023
            [Pseudomonas].
ACCESSION   WP_003113700
VERSION     WP_003113700.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 337)
  AUTHORS   Sivaraman,J., Li,Y., Banks,J., Cane,D.E., Matte,A. and Cygler,M.
  TITLE     Crystal structure of Escherichia coli PdxA, an enzyme involved in
            the pyridoxal phosphate biosynthesis pathway
  JOURNAL   J Biol Chem 278 (44), 43682-43690 (2003)
   PUBMED   12896974
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10011332
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..337
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..337
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /EC_number="1.1.1.262"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0050570 - 4-hydroxythreonine-4-phosphate
                     dehydrogenase activity [Evidence IEA]"
                     /GO_function="GO:0050897 - cobalt ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0042823 - pyridoxal phosphate biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=36190
     Region          3..337
                     /region_name="pdxA"
                     /note="4-hydroxythreonine-4-phosphate dehydrogenase;
                     Reviewed; PRK00232"
                     /db_xref="CDD:234696"
ORIGIN      
        1 mnapslprla mvlgdpagig peliarllad tevrekahiv liadeaemrr gmriagcefp
       61 yrridaletl dfadatpllh pwlsqggdef prseasavgg rysletlala leltrsgrtd
      121 ailfgplnkt slhmagmdhs delhwfaerl gfggpfcefn vlddlwtsrv tshvalaevp
      181 gllsqervge airliddalr rsglarprig vcglnphngd ngsfgreeld iiapavqkar
      241 eqgiaadgpy padtiflkvq gdarafdavv tmyhdqgqia iklmgfsrgv tvqgglpipi
      301 atpahgtafd iagqgradvg atrqafeiac rmgrhka