MULTISPECIES: EAL domain-containing protein [Pseudomonas].

LOCUS       WP_003113636             285 aa            linear   BCT 21-JAN-2025
ACCESSION   WP_003113636
VERSION     WP_003113636.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 285)
  AUTHORS   Chou,S.H. and Galperin,M.Y.
  TITLE     Diversity of Cyclic Di-GMP-Binding Proteins and Mechanisms
  JOURNAL   J Bacteriol 198 (1), 32-46 (2016)
   PUBMED   26055114
REFERENCE   2  (residues 1 to 285)
  AUTHORS   Schirmer,T. and Jenal,U.
  TITLE     Structural and mechanistic determinants of c-di-GMP signalling
  JOURNAL   Nat Rev Microbiol 7 (10), 724-735 (2009)
   PUBMED   19756011
REFERENCE   3  (residues 1 to 285)
  AUTHORS   Simm,R., Morr,M., Kader,A., Nimtz,M. and Romling,U.
  TITLE     GGDEF and EAL domains inversely regulate cyclic di-GMP levels and
            transition from sessility to motility
  JOURNAL   Mol Microbiol 53 (4), 1123-1134 (2004)
   PUBMED   15306016
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10112612
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..285
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..285
                     /product="EAL domain-containing protein"
                     /EC_number="3.1.4.52"
                     /GO_function="GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA]"
                     /calculated_mol_wt=31766
     Region          28..263
                     /region_name="EAL"
                     /note="EAL domain. This domain is found in diverse
                     bacterial signaling proteins. It is called EAL after its
                     conserved residues and is also known as domain of unknown
                     function 2 (DUF2). The EAL domain has been shown to
                     stimulate degradation of a second...; cd01948"
                     /db_xref="CDD:238923"
ORIGIN      
        1 mngspqarqh ehppavaasl agdlrlarrf qaalargrvr ldwqavrhag hpeweplyre
       61 tllrvtaasg epplptqeli lalerlglvr lldrcvlgtv ldrlnaeptl rlacnlsrqs
      121 aamdawweav crwlaarpqv arrltlelte tavgervatr efirrlrehg vriaiddfga
      181 ahnnldfvld arpdvikidc rytrearrsa kgaevlrhll alcrelapcv vlegleedda
      241 farlptgdvy lqgnaiappm rvepplsvrr pksrarieal asrqg