MULTISPECIES: methionine synthase [Pseudomonas].

LOCUS       WP_003113602            1234 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_003113602
VERSION     WP_003113602.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 1234)
  AUTHORS   Dixon,M.M., Huang,S., Matthews,R.G. and Ludwig,M.
  TITLE     The structure of the C-terminal domain of methionine synthase:
            presenting S-adenosylmethionine for reductive methylation of B12
  JOURNAL   Structure 4 (11), 1263-1275 (1996)
   PUBMED   8939751
REFERENCE   2  (residues 1 to 1234)
  AUTHORS   Drummond,J.T., Loo,R.R. and Matthews,R.G.
  TITLE     Electrospray mass spectrometric analysis of the domains of a large
            enzyme: observation of the occupied cobalamin-binding domain and
            redefinition of the carboxyl terminus of methionine synthase
  JOURNAL   Biochemistry 32 (36), 9282-9289 (1993)
   PUBMED   8369296
REFERENCE   3  (residues 1 to 1234)
  AUTHORS   Luschinsky,C.L., Drummond,J.T., Matthews,R.G. and Ludwig,M.L.
  TITLE     Crystallization and preliminary X-ray diffraction studies of the
            cobalamin-binding domain of methionine synthase from Escherichia
            coli
  JOURNAL   J Mol Biol 225 (2), 557-560 (1992)
   PUBMED   1593636
REFERENCE   4  (residues 1 to 1234)
  AUTHORS   Banerjee,R.V., Johnston,N.L., Sobeski,J.K., Datta,P. and
            Matthews,R.G.
  TITLE     Cloning and sequence analysis of the Escherichia coli metH gene
            encoding cobalamin-dependent methionine synthase and isolation of a
            tryptic fragment containing the cobalamin-binding domain
  JOURNAL   J Biol Chem 264 (23), 13888-13895 (1989)
   PUBMED   2668277
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007024.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09490
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1234
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..1234
                     /gene="metH"
     Protein         1..1234
                     /product="methionine synthase"
                     /EC_number="2.1.1.13"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008705 - methionine synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=134933
     Region          6..1231
                     /region_name="metH"
                     /note="B12-dependent methionine synthase; Provisional;
                     PRK09490"
                     /db_xref="CDD:236539"
ORIGIN      
        1 msspltdrsa rlqalqhalr erilildggm gtmiqsykle eadyrgerfa dwpsdvkgnn
       61 dllllsrpdv iqaiekayld agadiletnt fnatqvsqad ygmqslayel nvegarlarq
      121 vadaktaetp dkprfvagvl gptsrtcsis pdvnnpgyrn vtfdelveny veatrglieg
      181 gadlilieti fdtlnakaai favqgvfeel gvelpimisg titdasgrtl sgqtteafwn
      241 svrharpisv glncalgake lrpyieelst kadthvsahp naglpnafge ydespaemav
      301 vveefaaagf lnivggccgt tpahieaiak avakypprai peipracrls glepftidrs
      361 slfvnvgert nitgsakfar lireenyaea levaqqqvea gaqvidinmd egmldskaam
      421 vtflnliase pdisrvpimi dsskweviea glkciqgkgi vnsismkegv eafkhharlc
      481 krygaavvvm afdedgqadt qarkeeickr sydilvdevg fppediifda nifaiatgie
      541 ehnnyavdfi nacayirdnl pyalssggvs nvsfsfrgnn pvreaihsvf lyyairnglt
      601 mgivnagqle iydeipkalr drvedvvlnr tpeatealla iaddykggga vkeaedeewr
      661 sysvekrleh alvkgittwi vedteecrqq carpievieg plmsgmnvvg dlfgagkmfl
      721 pqvvksarvm kqavahlipf ieaekgdkpe akgkilmatv kgdvhdigkn ivgvvlgcng
      781 ydvvdlgvmv paekilqtai aekcdiigls glitpsldem vhvakemqrq nfqlplmigg
      841 attskahtav kidpqysnda vvyvtdasra vgvatsllsk elkadyvart radyavvrer
      901 tanrsarter lsyeqaiank pafdwagyqa ptpsftgvrv ldeidlavla eyidwtpffi
      961 swdlagkypr iltdevvgea atslfndaqa mlkklidekl ikaravfgfw panqvehddl
     1021 evygadgetl atlhhlrqqt ikpdgkpnls ladfvapkes gvrdyiggfi ttagigaeev
     1081 akayeakgdd ynsimvkala drlaeacaew lhervrkeyw gyardehldn ealikeqyvg
     1141 irpapgypac pdhtekgtlf elldpqglsg vsltehyamf paaavsgwyf ahpqaqyfav
     1201 gkidkdqver ysqrkgqeas vserwlapnl gydd