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LysR family transcriptional regulator [Pseudomonas aeruginosa].


LOCUS       WP_003113598             301 aa            linear   BCT 19-MAR-2023
ACCESSION   WP_003113598
VERSION     WP_003113598.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 301)
  AUTHORS   Maddocks,S.E. and Oyston,P.C.F.
  TITLE     Structure and function of the LysR-type transcriptional regulator
            (LTTR) family proteins
  JOURNAL   Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008)
   PUBMED   19047729
REFERENCE   2  (residues 1 to 301)
  AUTHORS   Schell,M.A.
  TITLE     Molecular biology of the LysR family of transcriptional regulators
  JOURNAL   Annu Rev Microbiol 47, 597-626 (1993)
   PUBMED   8257110
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10444042
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..301
                     /product="LysR family transcriptional regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /calculated_mol_wt=33339
     Region          4..63
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          92..288
                     /region_name="PBP2_LTTR_aromatics_like"
                     /note="The C-terminal substrate binding domain of
                     LysR-type transcriptional regulators involved in the
                     catabolism of aromatic compounds and that of other related
                     regulators, contains type 2 periplasmic binding fold;
                     cd08414"
                     /db_xref="CDD:176106"
     Site            order(97,104,107..108,110..111,114,122,124,126,171,
                     205..206,225..226,232..233,235..236,254)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:176106"
     Site            order(98,147,195..196,203)
                     /site_type="other"
                     /note="substrate binding pocket [chemical binding]"
                     /db_xref="CDD:176106"
ORIGIN      
        1 madlrqfrqf vavaeelsfr raaerlhmaq pplttairrl eeevgaslle rdnrihrltp
       61 agrafldear rtlaqaertl aaarsaasgr rtlrlafvds tinillpril qafrhqhgal
      121 dfqlqedtta gqlealredr idaglivlpv drqpglythl lvdgdmrval peghrlarha
      181 rlrleqlage pwllfprhyg pgmhdlivaa caaagfvpev vqearqmqti aglvaggigv
      241 alvpsllqpl rppgvtfrpl qgrraripyr lalayrtpse lierfretaq alaaapafrm
      301 a