MULTISPECIES: MFS transporter [Gammaproteobacteria].

LOCUS       WP_003113504             450 aa            linear   BCT 24-DEC-2024
ACCESSION   WP_003113504
VERSION     WP_003113504.1
KEYWORDS    RefSeq.
SOURCE      Gammaproteobacteria
  ORGANISM  Gammaproteobacteria
            Bacteria; Pseudomonadati; Pseudomonadota.
REFERENCE   1  (residues 1 to 450)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 450)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 450)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
REFERENCE   4  (residues 1 to 450)
  AUTHORS   Yan,N.
  TITLE     Structural advances for the major facilitator superfamily (MFS)
            transporters
  JOURNAL   Trends Biochem Sci 38 (3), 151-159 (2013)
   PUBMED   23403214
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024277
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Gammaproteobacteria"
                     /db_xref="taxon:1236"
     Protein         1..450
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=48014
     Region          33..434
                     /region_name="MFS_PcaK_like"
                     /note="4-hydroxybenzoate transporter PcaK and similar
                     transporters of the Major Facilitator Superfamily;
                     cd17365"
                     /db_xref="CDD:340923"
     Site            order(35..36,39..40,43,75,125..126,128..130,133,153,
                     156..157,160,262,265..266,269..271,274,301,305,356..357,
                     361,365,381,384..385,388..389,392)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340923"
ORIGIN      
        1 mhnqiasfra aldarpvsry qwllllllal llvtdgydaq vlgyvvptla qewgldkaaf
       61 gpvfsanlfg ltvgsllvtp ladrfgirrv llccvliyas ltvlmvfags leslmlarfv
      121 cgigmggamp samalmaeys pprlrtlmvt laacgfsfgg aaggfvaaaf mdgfgwqavf
      181 laggvtplll fpflllflpe slprllrdap pyarlrqlse rmapgwqppp aeadaepaas
      241 ltvlelfrhg yarptlllwa tffvslilly fmvswlpsll qesgltrnaa nlatsmflfa
      301 gtlgamllaw ladrlrskvr llaailagaa lftlllglnh dqprwllafv faagfciigg
      361 qltlnafasn fypaqvratg tgwalgvgrf gsilgplfgs lllgmhisve nifmlaaipa
      421 glaallilqv rspaaqaqre saaalavees