acetyl-CoA C-acetyltransferase [Pseudomonas aeruginosa].

LOCUS       WP_003113500             393 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_003113500
VERSION     WP_003113500.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 393)
  AUTHORS   Merilainen,G., Poikela,V., Kursula,P. and Wierenga,R.K.
  TITLE     The thiolase reaction mechanism: the importance of Asn316 and
            His348 for stabilizing the enolate intermediate of the Claisen
            condensation
  JOURNAL   Biochemistry 48 (46), 11011-11025 (2009)
   PUBMED   19842716
REFERENCE   2  (residues 1 to 393)
  AUTHORS   Igual,J.C., Gonzalez-Bosch,C., Dopazo,J. and Perez-Ortin,J.E.
  TITLE     Phylogenetic analysis of the thiolase family. Implications for the
            evolutionary origin of peroxisomes
  JOURNAL   J Mol Evol 35 (2), 147-155 (1992)
   PUBMED   1354266
REFERENCE   3  (residues 1 to 393)
  AUTHORS   LYNEN,F. and OCHOA,S.
  TITLE     Enzymes of fatty acid metabolism
  JOURNAL   Biochim Biophys Acta 12 (1-2), 299-314 (1953)
   PUBMED   13115439
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11481394
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..393
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..393
                     /product="acetyl-CoA C-acetyltransferase"
                     /GO_function="GO:0003985 - acetyl-CoA C-acetyltransferase
                     activity [Evidence IEA]"
                     /calculated_mol_wt=40274
     Region          1..393
                     /region_name="PRK05656"
                     /note="acetyl-CoA C-acetyltransferase"
                     /db_xref="CDD:168156"
ORIGIN      
        1 mqdvvivaat rtavgsfqgs lagipapelg aavirrlleq tgldagqvde vilgqvltag
       61 sgqnparqaa ikaglpvgvp amtlnkvcgs glkalhlgaq aircgdaevi vaggqenmsl
      121 apyvmpgart glrmghaklv dsmiedglwd afndyhmgit aenlaekygl treeqdafaa
      181 asqqkaiaai eggrfrdeit piqvpqrkge plgfdtdeqp ragttveala klkpafrkdg
      241 svtagnassl ndgaaavllm saakakalgl pvlariasya sagvdpaimg igpvsatrra
      301 ldkagwsleq ldlieaneaf aaqslavgre lgwdaarvnv nggaialghp igasgcrvlv
      361 tllhemirrd akkglatlci gggqgvaltl ard