MULTISPECIES: 23S rRNA pseudouridine(2605) synthase RluB

LOCUS       WP_003113439             386 aa            linear   BCT 10-MAR-2024
            [Pseudomonas].
ACCESSION   WP_003113439
VERSION     WP_003113439.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 386)
  AUTHORS   Czudnochowski,N., Ashley,G.W., Santi,D.V., Alian,A., Finer-Moore,J.
            and Stroud,R.M.
  TITLE     The mechanism of pseudouridine synthases from a covalent complex
            with RNA, and alternate specificity for U2605 versus U2604 between
            close homologs
  JOURNAL   Nucleic Acids Res 42 (3), 2037-2048 (2014)
   PUBMED   24214967
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF007976.1
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10700
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..386
                     /gene="rluB"
     Protein         1..386
                     /product="23S rRNA pseudouridine(2605) synthase RluB"
                     /EC_number="5.4.99.22"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis
                     [Evidence IEA]"
                     /calculated_mol_wt=43594
     Region          13..243
                     /region_name="RsuA"
                     /note="Pseudouridylate synthase RsuA, specific for 16S
                     rRNA U516 and 23S rRNA U2605 [Translation, ribosomal
                     structure and biogenesis]; COG1187"
                     /db_xref="CDD:440800"
     Region          265..>378
                     /region_name="PRK12678"
                     /note="transcription termination factor Rho; Provisional"
                     /db_xref="CDD:237171"
ORIGIN      
        1 mndtpenphv pvgeklqkvl arlgvgsrrd vevwiaegrv nvngsvaslg qrvdshdait
       61 vdghlirree aaesvrrvli ynkpegevct rddpegrpti fdrlprlrtg rwinvgrldi
      121 nttglllftt dgelanrlmh psyemdreya vrvrgevtee mierllngvm ledgpakfsd
      181 iqqapggegf nhwyhcvvme grnrevrrlw esqglvvsrl krvrfgpvfl tseltmgryr
      241 emdqreidil seevglkpva lpgmttkare kaerqqrkqa rplarserpe agrkraprre
      301 dgenaarrap asrpargpqp saerkgreqg tpvaerpres nrkprpskpr derpasapgd
      361 kpaarkpqvk rrpkpagdgm rpgfrr