MULTISPECIES: UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate oxidase

LOCUS       WP_003113428             316 aa            linear   BCT 17-AUG-2020
            [Pseudomonas].
ACCESSION   WP_003113428
VERSION     WP_003113428.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 316)
  AUTHORS   Thoden,J.B. and Holden,H.M.
  TITLE     Structural and functional studies of WlbA: A dehydrogenase involved
            in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic
            acid
  JOURNAL   Biochemistry 49 (36), 7939-7948 (2010)
   PUBMED   20690587
REFERENCE   2  (residues 1 to 316)
  AUTHORS   Larkin,A. and Imperiali,B.
  TITLE     Biosynthesis of UDP-GlcNAc(3NAc)A by WbpB, WbpE, and WbpD: enzymes
            in the Wbp pathway responsible for O-antigen assembly in
            Pseudomonas aeruginosa PAO1
  JOURNAL   Biochemistry 48 (23), 5446-5455 (2009)
   PUBMED   19348502
REFERENCE   3  (residues 1 to 316)
  AUTHORS   Westman,E.L., McNally,D.J., Charchoglyan,A., Brewer,D., Field,R.A.
            and Lam,J.S.
  TITLE     Characterization of WbpB, WbpE, and WbpD and reconstitution of a
            pathway for the biosynthesis of
            UDP-2,3-diacetamido-2,3-dideoxy-D-mannuronic acid in Pseudomonas
            aeruginosa
  JOURNAL   J. Biol. Chem. 284 (18), 11854-11862 (2009)
   PUBMED   19282284
REFERENCE   4  (residues 1 to 316)
  AUTHORS   Westman,E.L., Preston,A., Field,R.A. and Lam,J.S.
  TITLE     Biosynthesis of a rare di-N-acetylated sugar in the
            lipopolysaccharides of both Pseudomonas aeruginosa and Bordetella
            pertussis occurs via an identical scheme despite different gene
            clusters
  JOURNAL   J. Bacteriol. 190 (18), 6060-6069 (2008)
   PUBMED   18621892
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR012424
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..316
                     /gene="wbpB"
                     /gene_synonym="wlbA"
     Protein         1..316
                     /product="UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate
                     oxidase"
                     /EC_number="1.1.1.335"
                     /calculated_mol_wt=35586
     Region          1..255
                     /region_name="MviM"
                     /note="Predicted dehydrogenase [General function
                     prediction only]; COG0673"
                     /db_xref="CDD:440437"
     Region          141..309
                     /region_name="GFO_IDH_MocA_C"
                     /note="Oxidoreductase family, C-terminal alpha/beta
                     domain; pfam02894"
                     /db_xref="CDD:427044"
ORIGIN      
        1 mknfaligaa gyiaprhmra ikdtgnclvs aydindsvgi idsispqsef ftefeffldh
       61 asnlkrdsat aldyvsicsp nylhyphiaa glrlgcdvic ekplvptpem ldqlaviere
      121 tdkrlynilq lrhhqaiial kdkvareksp hkyevdltyi tsrgnwylks wkgdprksfg
      181 vatnigvhfy dmlhfifgkl qrnvvhftse ykaagyleye qarvrwflsv dandlpesvk
      241 gkkptyrsit vngeemefse gftdlhttsy eeilagrgyg iddarhcvet vntirsaviv
      301 pasdneghpf vaalar