MULTISPECIES: UDP-2-acetamido-3-amino-2,3-dideoxy-D-glucuronate

LOCUS       WP_003113426             191 aa            linear   BCT 17-AUG-2020
            N-acetyltransferase [Pseudomonas].
ACCESSION   WP_003113426
VERSION     WP_003113426.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 191)
  AUTHORS   Larkin,A. and Imperiali,B.
  TITLE     Biosynthesis of UDP-GlcNAc(3NAc)A by WbpB, WbpE, and WbpD: enzymes
            in the Wbp pathway responsible for O-antigen assembly in
            Pseudomonas aeruginosa PAO1
  JOURNAL   Biochemistry 48 (23), 5446-5455 (2009)
   PUBMED   19348502
REFERENCE   2  (residues 1 to 191)
  AUTHORS   Westman,E.L., McNally,D.J., Charchoglyan,A., Brewer,D., Field,R.A.
            and Lam,J.S.
  TITLE     Characterization of WbpB, WbpE, and WbpD and reconstitution of a
            pathway for the biosynthesis of
            UDP-2,3-diacetamido-2,3-dideoxy-D-mannuronic acid in Pseudomonas
            aeruginosa
  JOURNAL   J. Biol. Chem. 284 (18), 11854-11862 (2009)
   PUBMED   19282284
REFERENCE   3  (residues 1 to 191)
  AUTHORS   Wenzel,C.Q., Daniels,C., Keates,R.A., Brewer,D. and Lam,J.S.
  TITLE     Evidence that WbpD is an N-acetyltransferase belonging to the
            hexapeptide acyltransferase superfamily and an important protein
            for O-antigen biosynthesis in Pseudomonas aeruginosa PAO1
  JOURNAL   Mol. Microbiol. 57 (5), 1288-1303 (2005)
   PUBMED   16102001
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR012425
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..191
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..191
                     /gene="wbpD"
     Protein         1..191
                     /product="UDP-2-acetamido-3-amino-2,
                     3-dideoxy-D-glucuronate N-acetyltransferase"
                     /EC_number="2.3.1.201"
                     /calculated_mol_wt=20431
     Region          35..153
                     /region_name="LbH_WxcM_N_like"
                     /note="WcxM-like, Left-handed parallel beta-Helix (LbH)
                     N-terminal domain: This group is composed of Xanthomonas
                     campestris WcxM and proteins with similarity to the WcxM
                     N-terminal domain. WcxM is thought to be bifunctional,
                     catalyzing both the isomerization...; cd03358"
                     /db_xref="CDD:100048"
     Site            order(56,58,66,74,76,82,88..90,107,109,112,131,147)
                     /site_type="other"
                     /note="putative trimer interface [polypeptide binding]"
                     /db_xref="CDD:100048"
     Site            order(58,60,88,90,109,111..112,117,129..130,135..136,
                     145..146,148)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:100048"
     Site            order(58,60,88)
                     /site_type="other"
                     /note="putative substrate binding site [chemical binding]"
                     /db_xref="CDD:100048"
     Site            order(88,90,109,111..112,117,127,129..130,135..136,143,
                     145..146,148,152)
                     /site_type="other"
                     /note="putative CoA binding site [chemical binding]"
                     /db_xref="CDD:100048"
ORIGIN      
        1 msyyqhpsai vddgaqigsd srvwhfvhic agarigagvs lgqnvfvgnk vvigdrckiq
       61 nnvsvydnvt leegvfcgps mvftnvynpr slierkdqyr ntlvkkgatl ganctivcgv
      121 tigeyafvga gavinknvps yalmvgvpar qigwmsefge qlqlneqgea vcshsgaryv
      181 lngkilskvd v