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MULTISPECIES: dihydro-heme d1 dehydrogenase [Pseudomonas].


LOCUS       WP_003113244             493 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_003113244
VERSION     WP_003113244.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 493)
  AUTHORS   Klunemann,T., Preuss,A., Adamczack,J., Rosa,L.F.M., Harnisch,F.,
            Layer,G. and Blankenfeldt,W.
  TITLE     Crystal Structure of Dihydro-Heme d1 Dehydrogenase NirN from
            Pseudomonas aeruginosa Reveals Amino Acid Residues Essential for
            Catalysis
  JOURNAL   J Mol Biol 431 (17), 3246-3260 (2019)
   PUBMED   31173777
REFERENCE   2  (residues 1 to 493)
  AUTHORS   Adamczack,J., Hoffmann,M., Papke,U., Haufschildt,K., Nicke,T.,
            Broring,M., Sezer,M., Weimar,R., Kuhlmann,U., Hildebrandt,P. and
            Layer,G.
  TITLE     NirN protein from Pseudomonas aeruginosa is a novel
            electron-bifurcating dehydrogenase catalyzing the last step of heme
            d1 biosynthesis
  JOURNAL   J Biol Chem 289 (44), 30753-30762 (2014)
   PUBMED   25204657
REFERENCE   3  (residues 1 to 493)
  AUTHORS   Nicke,T., Schnitzer,T., Munch,K., Adamczack,J., Haufschildt,K.,
            Buchmeier,S., Kucklick,M., Felgentrager,U., Jansch,L., Riedel,K.
            and Layer,G.
  TITLE     Maturation of the cytochrome cd1 nitrite reductase NirS from
            Pseudomonas aeruginosa requires transient interactions between the
            three proteins NirS, NirN and NirF
  JOURNAL   Biosci Rep 33 (3), e00048 (2013)
   PUBMED   23683062
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR013475
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..493
                     /gene="nirN"
     Protein         1..493
                     /product="dihydro-heme d1 dehydrogenase"
                     /calculated_mol_wt=53847
     Region          <21..79
                     /region_name="CccA"
                     /note="Cytochrome c, mono- and diheme variants [Energy
                     production and conversion]; COG2010"
                     /db_xref="CDD:441613"
     Region          100..483
                     /region_name="8prop_heme-binding_NirN"
                     /note="eight-bladed heme d1-binding beta-propeller domain
                     in dihydro-heme d1 dehydrogenase NirN; cd20777"
                     /db_xref="CDD:467721"
     Site            order(113,214,216..217,232,264,281..282)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:467721"
     Region          129..160
                     /region_name="propeller blade"
                     /note="propeller blade [structural motif]"
                     /db_xref="CDD:467721"
     Region          162..201
                     /region_name="propeller blade"
                     /note="propeller blade [structural motif]"
                     /db_xref="CDD:467721"
     Region          162..201
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Site            order(164..167,169,182,207..208,256,258,300,341,361,435,
                     450,476..477,479)
                     /site_type="other"
                     /note="heme D binding site [chemical binding]"
                     /db_xref="CDD:467721"
     Region          205..244
                     /region_name="propeller blade"
                     /note="propeller blade [structural motif]"
                     /db_xref="CDD:467721"
     Region          208..246
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          254..293
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          256..293
                     /region_name="propeller blade"
                     /note="propeller blade [structural motif]"
                     /db_xref="CDD:467721"
     Region          294..334
                     /region_name="propeller blade"
                     /note="propeller blade [structural motif]"
                     /db_xref="CDD:467721"
     Region          335..382
                     /region_name="propeller blade"
                     /note="propeller blade [structural motif]"
                     /db_xref="CDD:467721"
     Region          384..427
                     /region_name="propeller blade"
                     /note="propeller blade [structural motif]"
                     /db_xref="CDD:467721"
     Region          429..471
                     /region_name="propeller blade"
                     /note="propeller blade [structural motif]"
                     /db_xref="CDD:467721"
ORIGIN      
        1 mrliglalgl llgalaqage apgealyrqh cqachgagrl ggsgptllpe slsrlkpaqa
       61 revilhgrpa tqmagfagql ddaaadalva ylyqapprep qwsaediras qvqphplatl
      121 psrprfeadp lnlfvvvesg dhhvtildgd rfepiarfps ryalhggpkf spdgrlvyfa
      181 srdgwvtlyd lynlkvvaev raglntrnla vsddgrwvlv gnylpgnlvl ldardlslvq
      241 vipaadaqgq asrvsavyta pprhsfvval kdvhelwelp yangkpvapk rlavadyldd
      301 fsfspdyryl lgssrqargg evieldsgar vasiplsgmp hlgsgiywkr dgrwvfatpn
      361 isrgvisvid lqnwkplkei vtdgpgffmr shadspyawt dtflgkkhde illidkqtle
      421 iahrlrpspg kvaghveftr dgryallsvw drdgalvvyd ahsleevkrl pmnkpsgkyn
      481 vgnkigyaeg tsh