MULTISPECIES: ArsR/SmtB family transcription factor [Pseudomonas].

LOCUS       WP_003113231             333 aa            linear   BCT 24-DEC-2024
ACCESSION   WP_003113231
VERSION     WP_003113231.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 333)
  AUTHORS   Roy,R., Samanta,S., Patra,S., Mahato,N.K. and Saha,R.P.
  TITLE     In silico identification and characterization of sensory motifs in
            the transcriptional regulators of the ArsR-SmtB family
  JOURNAL   Metallomics 10 (10), 1476-1500 (2018)
   PUBMED   30191942
REFERENCE   2  (residues 1 to 333)
  AUTHORS   Saha,R.P., Samanta,S., Patra,S., Sarkar,D., Saha,A. and Singh,M.K.
  TITLE     Metal homeostasis in bacteria: the role of ArsR-SmtB family of
            transcriptional repressors in combating varying metal
            concentrations in the environment
  JOURNAL   Biometals 30 (4), 459-503 (2017)
   PUBMED   28512703
REFERENCE   3  (residues 1 to 333)
  AUTHORS   Ren,S., Li,Q., Xie,L. and Xie,J.
  TITLE     Molecular Mechanisms Underlying the Function Diversity of ArsR
            Family Metalloregulator
  JOURNAL   Crit Rev Eukaryot Gene Expr 27 (1), 19-35 (2017)
   PUBMED   28436329
REFERENCE   4  (residues 1 to 333)
  AUTHORS   Aravind,L., Anantharaman,V., Balaji,S., Babu,M.M. and Iyer,L.M.
  TITLE     The many faces of the helix-turn-helix domain: transcription
            regulation and beyond
  JOURNAL   FEMS Microbiol Rev 29 (2), 231-262 (2005)
   PUBMED   15808743
REFERENCE   5  (residues 1 to 333)
  AUTHORS   Busenlehner,L.S., Pennella,M.A. and Giedroc,D.P.
  TITLE     The SmtB/ArsR family of metalloregulatory transcriptional
            repressors: Structural insights into prokaryotic metal resistance
  JOURNAL   FEMS Microbiol Rev 27 (2-3), 131-143 (2003)
   PUBMED   12829264
REFERENCE   6  (residues 1 to 333)
  AUTHORS   Schubert,H.L., Blumenthal,R.M. and Cheng,X.
  TITLE     Many paths to methyltransfer: a chronicle of convergence
  JOURNAL   Trends Biochem Sci 28 (6), 329-335 (2003)
   PUBMED   12826405
REFERENCE   7  (residues 1 to 333)
  AUTHORS   Rosinski,J.A. and Atchley,W.R.
  TITLE     Molecular evolution of helix-turn-helix proteins
  JOURNAL   J Mol Evol 49 (3), 301-309 (1999)
   PUBMED   10473770
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 18827174
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..333
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..333
                     /product="ArsR/SmtB family transcription factor"
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=35972
     Region          16..81
                     /region_name="HTH_metalloreg"
                     /note="metalloregulator ArsR/SmtB family transcription
                     factor; NF033788"
                     /db_xref="CDD:411368"
     Site            order(21..22,26..28,41..43,52..55,57..58,61..62,64..65,
                     71..73,78..80)
                     /site_type="other"
                     /note="putative DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238042"
     Region          130..287
                     /region_name="UbiE"
                     /note="Ubiquinone/menaquinone biosynthesis C-methylase
                     UbiE/MenG [Coenzyme transport and metabolism]; COG2226"
                     /db_xref="CDD:441828"
ORIGIN      
        1 mslrvpsirp ddydplaalc kaagdslrln vlralandsf gvlelaqifa igqsgmshhl
       61 kvlaqaglva trregnaify rrslplaert ggalhaalle evderalpdd vraridavha
      121 qraavsqdff araadkfqaq qdliaglpqy resvlallda lafapgatal evgpgdggfl
      181 pelarrfrqv taldnsaaml elarqrckee glgnvrlela dalqdaaepa dcvvlnmvlh
      241 hfaapaealk qlarlvhpgg sllvtdlcrh nqgwareacg dlwlgfeqed laqwadaagl
      301 tpgeslyigl rngfqiqvrh fardasesrl thr