amino acid adenylation domain-containing protein [Pseudomonas

LOCUS       WP_003113143            2352 aa            linear   BCT 24-DEC-2024
            aeruginosa].
ACCESSION   WP_003113143
VERSION     WP_003113143.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 2352)
  AUTHORS   Konz,D. and Marahiel,M.A.
  TITLE     How do peptide synthetases generate structural diversity?
  JOURNAL   Chem Biol 6 (2), R39-R48 (1999)
   PUBMED   10021423
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01733.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2352
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..2352
                     /product="amino acid adenylation domain-containing
                     protein"
                     /calculated_mol_wt=259276
     Region          4..>2072
                     /region_name="PRK12467"
                     /note="peptide synthase; Provisional"
                     /db_xref="CDD:237108"
     Region          2077..2341
                     /region_name="alpha/beta hydrolases"
                     /note="A functionally diverse superfamily containing
                     proteases, lipases, peroxidases, esterases, epoxide
                     hydrolases and dehalogenases. The catalytic apparatus
                     typically involves three residues (catalytic triad): a
                     serine, a glutamate or aspartate and a...; cl21494"
                     /db_xref="CDD:473884"
ORIGIN      
        1 mvrfarlpls pyqrdiwvaa aqfpeldqyt ifsydrftge vdtqaleral lqaardteaf
       61 rlrlgetdgt pyqwldtdae fearhvdlra drdpeaavrs wlrdafrhay pldgrslvdl
      121 allhsdqaly vyvrthhivs dawglqlfls rvragylgel gepqaqmpta sllaqletdd
      181 ysgseqyrgd rayfaealeg lepalftrrr paglrrtarh rltlertlld airdrgespf
      241 lflsaavaly larihqnddv vlgvpvlnra draakqvvgh fantlplrir tapeqtvdef
      301 laqlreatrt llrhqkmplg dllrgasplf dttlsymrwp aaqaipnasv etvaqthahd
      361 pdalaiwvse fdghsdaqvd feyacdvfda dfpmdaaarh ietflralve ggerrlgeld
      421 plsaaereel ihtrnatdqa fpeqatlptl faeqvartpq rtalleadgg tlsyaeldak
      481 vqavadalra agvrtderva llvargphll pailgvqrag gayvpinpdh plervrllle
      541 dcgarvvlvd eraatlgesl getrvlhler lpqstgdlpa anvapgdlay viytsgstgm
      601 pkgvmvehrs vvnrlnwmqr rypigerdvl lqktpvtfdv svwelfwwsf tgarlsllpp
      661 gaekdpreml rsiqrdavtv ihfvpsmltp fldlldgdpt araaasslrl vfcsgealap
      721 lqvarfrrlf gdavrlvnly gpteatvdvs dhecasdnpt rvpigrpidn lrlyvldral
      781 rpqplgavge lyiggvgvar gylnrpelna erflvdpfva ggrlyrtgdl arwladgnle
      841 ylgraddqvk irgnrvepde vrdrlaalpg vrdaavvard savrgthlvg yyvaaaeldp
      901 gqlraglsat lpdfmlpaff vridslplsa ngkldrrqlp appeqvaava prtateaela
      961 avwadvlgva evgvhddfya lggdsilmlr iraaaqrrgl gfeladlmrn ptvaglaerl
     1021 vrplaersyq pfelvsevdk prlegledaf ptsrlslgll fhsrqrpdss vyhdvfhyrf
     1081 dlawdeaafr haldrvvaay palrssfdls gaseplqlvh tqarseplil dlrgnpeagt
     1141 vldehirqrr fhryslqqpg lflfaafvre dgldlvfsfh haildgwsva nlivalvaay
     1201 rgeplpgpap alachvreel aalaspaavg ywtgllegar mtrldgfgah epqaaqgpas
     1261 hrealpdgll erlkataaqr glplksllla ahcltlhlfs rsdsvvtgai sngrpelpda
     1321 drmvglflnt vpvrseiagc swievadalf rqerdghahr ryplsaiqqi vgdelssafn
     1381 yvnlhvlepl wqlrdfrvwe etnfallvnv iatpsdgmyl ridsdgrgis rsqaaligat
     1441 fvellwrlad hpdeaadfaf laprrdaasq peplvdvvsl ferqvealpg saalafeeqr
     1501 wtyrdldhva rcvatrlvra garrgdaigv alnrspemia tiwgilragl vcvpldvsyp
     1561 aqrlalilet aqpfrvvahp ehahvaaaer vlpveelvad iepetfaapq ldelamllft
     1621 sgstgrpkgv elshrmwany tqwqlrvasg vpglrtlqfa plsfdmafqe ifstlcggge
     1681 lqlisnrerm dpsallhvle rrqvqrvllp fvalqrlaea snalgvrpga lrvvvssgeq
     1741 lritedvraf caampgllle nqygptethq vtyhslsgdp ahypdlppig rpldgvevqv
     1801 ldaalrpvpv gvtgelyfgg dclargyhra pkltaerfve hpwrpgarly rtgdlgrilg
     1861 ngeivwlgra dtqvkvrgfr iepaevelai mrqaerqpgl rgaavvarer qgndaflaaf
     1921 llgepeavdl aelkqalrse lpehmvpahf awvdgfaltp sgkrddaalr alplehgtni
     1981 eylaprddye rtlagllgel ldrprvgird sffdlggtsl samrfmllie krygvdlpma
     2041 alietptveg laerlrersa vrafdplvpi raggsrpplf lvhplgghvl cylplvralp
     2101 pdqpvyalqa agtgqgstpl avlediaasy laairrvqpe gpyylggwsf ggfvayemar
     2161 qlraldpqav aqlivldsit vdrnhagsas dealllffyw elvwfersdk eveplpegas
     2221 leqkldhive raieagvlpa gtpratvqrl yelfraswqa ligyrpevsd qdmtllradg
     2281 plplalkpmh daagthygdp kngwqhwtsg rldvidvpgd hlvlmkepyv etvaaeiaal
     2341 lepstssert rp