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non-ribosomal peptide synthetase [Pseudomonas aeruginosa].


LOCUS       WP_003113094            1249 aa            linear   BCT 28-JUL-2019
ACCESSION   WP_003113094
VERSION     WP_003113094.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13483606
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1249
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..1249
                     /product="non-ribosomal peptide synthetase"
                     /calculated_mol_wt=134317
     Region          192..>1236
                     /region_name="PRK12467"
                     /note="peptide synthase; Provisional"
                     /db_xref="CDD:237108"
     Region          241..721
                     /region_name="A_NRPS_Sfm_like"
                     /note="The adenylation domain of nonribosomal peptide
                     synthetases (NRPS), including Saframycin A gene cluster
                     from Streptomyces lavendulae; cd12115"
                     /db_xref="CDD:341280"
     Site            order(385,388..393,395..396)
                     /site_type="other"
                     /note="acyl-activating enzyme (AAE) consensus motif"
                     /db_xref="CDD:341280"
     Site            order(388..389,497..498,519..524,547,611,623,626,715)
                     /site_type="other"
                     /note="AMP binding site [chemical binding]"
                     /db_xref="CDD:341280"
ORIGIN      
        1 mqerhglplr sfssgkalta gravrpevaq errylqgapl glelpgrial rdphcawqwf
       61 epeaaaeafp aahwlaaflv llgrygneei tlgfpepitv rgrqapallr ssyramessa
      121 ersarlaeel ddarrqlsad gqeraalagr cavqvlaarp tasspgwlal vlaadgsvgl
      181 alrdpqydel rriaghlarl arglvdaqac vgrlpwldad eerrlqalrs epqaapsrgv
      241 lhhlfeaqar rtpqriavha adrslsyael eresaalavr lraagvapeq rvgvclrrds
      301 gllvgllgvl raggcyvpld paypeervay mlddadcllv lvdastrerv aalgrpcltl
      361 eeggdqandl alpasevgad hlayiiytsg stgrpkgvai ehgsahaflr wagqhyaaee
      421 wsgvlaatsv cfdlsvyelf gtlaeggtlh lvenlfslpd yprrdeisll ntvpsvcaal
      481 lalgdlpggv rtlnlagepl rghlvrqirg qpqvrrlvnl ygptedttys tvheldlhae
      541 aldeppigrp lpgttvevld gfeaplplgv agelylggig largyfgkpe qtaerfrvdp
      601 gsgerryrtg drvrmredgv lehlgrlddq vkfngfriel geiasclasf pgvseacaml
      661 tedsaglrrl vgylaapfap plqalnehlg qslphymlps afvvlaelpk tlngkidrka
      721 lprpqatgae pqalpsdple qalhqawqaq lgappragqg fyaaggdslr avhllatlrq
      781 rlsrrvplqa faggpatpea llellrqaap egdepepsag aaglslaerr lwvaqqlape
      841 dtsynllahl rivgatadai eqalrqller hvalrrrvet gvdgpqphal aahavplqrl
      901 lasdavhaer lledgvrreg arvfdlahea parlllvvtr dsaradllls vhhyafddvs
      961 lavfaaelkt lldggrlgvl astpeqvaar eraalasgrl drvaerwaer llplakapga
     1021 aparpeesgg ragqrlalpv saavhaacra laertsvspf saalqafaev lgaelgvddl
     1081 lvgvalagrs rlemqglvgc fvnllplavg lrpeqsvewr lrqvghdlle llehqdvple
     1141 cvtqalrqrg asglpiriac gahngraapa vdagvrvead fipvpgarld ltlwledqpq
     1201 gwlavwtgvs aifdlhrier lhqawerrll anagepiskr mspegcnas