MFS transporter [Pseudomonas aeruginosa].

LOCUS       WP_003113088             417 aa            linear   BCT 28-JUL-2024
ACCESSION   WP_003113088
VERSION     WP_003113088.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 417)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 417)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023516
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..417
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..417
                     /product="MFS transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=43253
     Region          27..391
                     /region_name="MFS_NepI_like"
                     /note="Purine ribonucleoside efflux pump NepI and similar
                     transporters of the Major Facilitator Superfamily;
                     cd17324"
                     /db_xref="CDD:340882"
     Site            order(37..38,41..42,45,77,127..128,130..132,135,155,
                     158..159,162,230,233..234,237..239,242,268,272,321..322,
                     326,330,345,348..349,352..353,356)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340882"
ORIGIN      
        1 mgrreafpen agaaasavap rlplsallam amsgfvails etlpagllpq igaglavsea
       61 lagqlvsvya lgsllaalpa asltqgwrrr rvlllallif fvcnsftavs sdyrltllar
      121 fgsgvaagla wgllagyarr lvppeqqgra lavamlgapl alslgvplgt wlggllgwrw
      181 afgllsltal llvgwvlrsv pdfpgqpagr rlrllgvlrt pgvrpvllvi vawvlahnil
      241 ytyiapflak vglgasvdla llvfgsaava giwlvgvlvd rhlrrmvlas lalfavaala
      301 lclgarwswl afaglalwgl tfggaatllq tasadaageg adlaqsmivv awnlaiaggg
      361 alggmvlqrw gsemlpwtll pliglaavlv wgnaahafrv gprdfrrass ehrkaaq