MULTISPECIES: LysR family transcriptional regulator [Pseudomonas].

LOCUS       WP_003113086             297 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_003113086
VERSION     WP_003113086.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 297)
  AUTHORS   Maddocks,S.E. and Oyston,P.C.F.
  TITLE     Structure and function of the LysR-type transcriptional regulator
            (LTTR) family proteins
  JOURNAL   Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008)
   PUBMED   19047729
REFERENCE   2  (residues 1 to 297)
  AUTHORS   Felder,C.B., Graul,R.C., Lee,A.Y., Merkle,H.P. and Sadee,W.
  TITLE     The Venus flytrap of periplasmic binding proteins: an ancient
            protein module present in multiple drug receptors
  JOURNAL   AAPS PharmSci 1 (2), E2 (1999)
   PUBMED   11741199
REFERENCE   3  (residues 1 to 297)
  AUTHORS   Schell,M.A.
  TITLE     Molecular biology of the LysR family of transcriptional regulators
  JOURNAL   Annu Rev Microbiol 47, 597-626 (1993)
   PUBMED   8257110
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10444117
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..297
                     /product="LysR family transcriptional regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=33151
     Region          9..62
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          92..288
                     /region_name="PBP2_CrgA_like_7"
                     /note="The C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator
                     CrgA-like, contains the type 2 periplasmic binding fold;
                     cd08476"
                     /db_xref="CDD:176165"
     Site            order(100,104,143,157,159,223,240,267)
                     /site_type="active"
                     /note="putative effector binding pocket [active]"
                     /db_xref="CDD:176165"
     Site            order(101..102,106..107,109..110,113,117,119..125,186,
                     217..221,228..229,232)
                     /site_type="other"
                     /note="putative dimerization interface [polypeptide
                     binding]"
                     /db_xref="CDD:176165"
ORIGIN      
        1 mdslsgftvf vrvaetrsiv gaartlgvsa savgkrvarl eeklgvrlfh rstrsitlta
       61 egslflersr rilaeieate lelsqsretp rgrlrvslpl vsglvlptla dfmqaypdie
      121 ldldfsdrvv dvvdegfdvv lrtgqpvdsr lsmrelgefq lklvgspayf arhgtprcpe
      181 dllrhtclhy rfpntgrlee wplrradgea ppqipvsmvc nnietrvcfa lrdqgiaclp
      241 dfsirealre grlvsvldaf cerraqffll wpsgrqvspk lrafidfvap rviatlg