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MULTISPECIES: protease modulator HflC [Pseudomonas].


LOCUS       WP_003113077             341 aa            linear   BCT 23-JUL-2024
ACCESSION   WP_003113077
VERSION     WP_003113077.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 341)
  AUTHORS   Bandyopadhyay,K., Parua,P.K., Datta,A.B. and Parrack,P.
  TITLE     Studies on Escherichia coli HflKC suggest the presence of an
            unidentified lambda factor that influences the lysis-lysogeny
            switch
  JOURNAL   BMC Microbiol 11, 34 (2011)
   PUBMED   21324212
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 341)
  AUTHORS   Bandyopadhyay,K., Parua,P.K., Datta,A.B. and Parrack,P.
  TITLE     Escherichia coli HflK and HflC can individually inhibit the HflB
            (FtsH)-mediated proteolysis of lambdaCII in vitro
  JOURNAL   Arch Biochem Biophys 501 (2), 239-243 (2010)
   PUBMED   20599668
REFERENCE   3  (residues 1 to 341)
  AUTHORS   Browman,D.T., Hoegg,M.B. and Robbins,S.M.
  TITLE     The SPFH domain-containing proteins: more than lipid raft markers
  JOURNAL   Trends Cell Biol 17 (8), 394-402 (2007)
   PUBMED   17766116
REFERENCE   4  (residues 1 to 341)
  AUTHORS   Briere,L.K. and Dunn,S.D.
  TITLE     The periplasmic domains of Escherichia coli HflKC oligomerize
            through right-handed coiled-coil interactions
  JOURNAL   Biochemistry 45 (28), 8607-8616 (2006)
   PUBMED   16834335
REFERENCE   5  (residues 1 to 341)
  AUTHORS   Tavernarakis,N., Driscoll,M. and Kyrpides,N.C.
  TITLE     The SPFH domain: implicated in regulating targeted protein turnover
            in stomatins and other membrane-associated proteins
  JOURNAL   Trends Biochem Sci 24 (11), 425-427 (1999)
   PUBMED   10542406
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10130459
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..341
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..341
                     /gene="hflC"
     Protein         1..341
                     /product="protease modulator HflC"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0098797 - plasma membrane protein
                     complex [Evidence IEA]"
                     /GO_process="GO:0052547 - regulation of peptidase activity
                     [Evidence IEA]"
                     /calculated_mol_wt=37213
     Region          52..312
                     /region_name="SPFH_HflC"
                     /note="High frequency of lysogenization C (HflC) family;
                     SPFH (stomatin, prohibitin, flotillin, and HflK/C)
                     superfamily; cd03405"
                     /db_xref="CDD:259803"
ORIGIN      
        1 mslghshshs hhehhhdhdh dhdhghgaqa aspwrrllva allvlfavaa aclvqvrsge
       61 amvitrfgnp arvllepgla wrlplpfesa ipvdlrlrtt ssglqdvgtr dglriivqay
      121 vawqvqgdad nvqrfmravr nqpdeaarql rtfvgsalet tasaydladl vnteasrvri
      181 gdfearlreq idhqllatyg vkvvqvgier ltlpkvtlga tvdrmraere tiatertaeg
      241 rrqaaeirsa aerdarviqa easvkaaeie aqarveaari ygkayagspq lynllrsldt
      301 lgtivngdtr lvlrtdaapf rvlvdgppal paeapangrr p