MULTISPECIES: cyclic di-GMP phosphodiesterase [Pseudomonas].

LOCUS       WP_003113015             414 aa            linear   BCT 22-AUG-2022
ACCESSION   WP_003113015
VERSION     WP_003113015.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 414)
  AUTHORS   Stelitano,V., Giardina,G., Paiardini,A., Castiglione,N.,
            Cutruzzola,F. and Rinaldo,S.
  TITLE     C-di-GMP hydrolysis by Pseudomonas aeruginosa HD-GYP
            phosphodiesterases: analysis of the reaction mechanism and novel
            roles for pGpG
  JOURNAL   PLoS One 8 (9), e74920 (2013)
   PUBMED   24066157
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 414)
  AUTHORS   Ryan,R.P., Lucey,J., O'Donovan,K., McCarthy,Y., Yang,L.,
            Tolker-Nielsen,T. and Dow,J.M.
  TITLE     HD-GYP domain proteins regulate biofilm formation and virulence in
            Pseudomonas aeruginosa
  JOURNAL   Environ Microbiol 11 (5), 1126-1136 (2009)
   PUBMED   19170727
  REMARK    Erratum:[Environ Microbiol. 2016 Feb;18(2):736. PMID: 26913821]
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR013058
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..414
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..414
                     /product="cyclic di-GMP phosphodiesterase"
                     /calculated_mol_wt=45289
     Region          2..126
                     /region_name="DUF3391"
                     /note="Domain of unknown function (DUF3391); pfam11871"
                     /db_xref="CDD:432148"
     Region          <102..329
                     /region_name="HDGYP"
                     /note="HD-GYP domain, c-di-GMP phosphodiesterase class II
                     (or its inactivated variant) [Signal transduction
                     mechanisms]; COG2206"
                     /db_xref="CDD:441808"
ORIGIN      
        1 mlkripvtql rlgmfvqslc gswldhpfwk rggflldsqa dlqrlresav kevwidaskg
       61 ldlpeeaavs aaavlpvtmp agpsparval eeeirhaall csrakaavvs mfrdarmgqa
      121 idtahasdlv deisasvlrh pnallslvrl ktsdeytymh svavcalmia larqlelpdp
      181 lvreaglagl lhdigkmavp dpilnkpgkl tdpefglvrr hpqngarmll dcrqvsalvv
      241 dvclhhheri dgtgypfgla qeqisllarm gavcdvydai tsdrpykkgw naaeairrma
      301 ewnghfdpqv frafvkavgi ypvgalvrle sgrlgvvleq hgrslltprv kvffsarskv
      361 pipqqvvdlg ragqtdrivg fepaeawnfr nldemwtgla kstgsyfdag tgnp