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protease IV [Pseudomonas aeruginosa].


LOCUS       WP_003112986             462 aa            linear   BCT 10-JUL-2019
ACCESSION   WP_003112986
VERSION     WP_003112986.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 462)
  AUTHORS   Oh,J., Li,X.H., Kim,S.K. and Lee,J.H.
  TITLE     Post-secretional activation of Protease IV by quorum sensing in
            Pseudomonas aeruginosa
  JOURNAL   Sci Rep 7 (1), 4416 (2017)
   PUBMED   28667333
REFERENCE   2  (residues 1 to 462)
  AUTHORS   Thibodeaux,B.A., Caballero,A.R., Dajcs,J.J., Marquart,M.E.,
            Engel,L.S. and O'Callaghan,R.J.
  TITLE     Pseudomonas aeruginosa protease IV: a corneal virulence factor of
            low immunogenicity
  JOURNAL   Ocul. Immunol. Inflamm. 13 (2-3), 169-182 (2005)
   PUBMED   16019676
REFERENCE   3  (residues 1 to 462)
  AUTHORS   Caballero,A., Thibodeaux,B., Marquart,M., Traidej,M. and
            O'Callaghan,R.
  TITLE     Pseudomonas keratitis: protease IV gene conservation, distribution,
            and production relative to virulence and other Pseudomonas
            proteases
  JOURNAL   Invest. Ophthalmol. Vis. Sci. 45 (2), 522-530 (2004)
   PUBMED   14744894
REFERENCE   4  (residues 1 to 462)
  AUTHORS   Wilderman,P.J., Vasil,A.I., Johnson,Z., Wilson,M.J., Cunliffe,H.E.,
            Lamont,I.L. and Vasil,M.L.
  TITLE     Characterization of an endoprotease (PrpL) encoded by a
            PvdS-regulated gene in Pseudomonas aeruginosa
  JOURNAL   Infect. Immun. 69 (9), 5385-5394 (2001)
   PUBMED   11500408
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR005319
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     gene            1..462
                     /gene="piv"
     Protein         1..462
                     /product="protease IV"
                     /EC_number="3.4.21.50"
                     /calculated_mol_wt=48082
     Region          245..420
                     /region_name="eMpr"
                     /note="V8-like Glu-specific endopeptidase
                     [Posttranslational modification, protein turnover,
                     chaperones]; COG3591"
                     /db_xref="CDD:442810"
ORIGIN      
        1 mhkrtylnac lvlalaagas qalaapgase magdvavlqa spastgharf anpnaaisaa
       61 gihfaappar rvaraaplap kpgtplqvgv glktatpeid lttlewidtp dgrhtarfpi
      121 saagaaslra airlethsgs lpddvllhfa gagkeifeas gkdlsvnrpy wspviegdtl
      181 tvelvlpanl qpgdlrlsvp qvsyfadsly kagyrdgfga sgscevdavc atqsgtrayd
      241 nataavakmv ftssadggsy ictgtllnng nspkrqlfws aahciedqat aatlqtiwfy
      301 nttqcygdas tinqsvtvlt gganilhrda krdtlllelk rtppagvfyq gwsatpiang
      361 slghdihhpr gdakkysqgn vsavgvtydg htaltrvdwp savveggssg sglltvagdg
      421 syqlrgglyg gpsycgapts qrndyfsdfs gvysqisryf ap