PepSY domain-containing protein [Pseudomonas aeruginosa].

LOCUS       WP_003112851             850 aa            linear   BCT 01-MAR-2025
ACCESSION   WP_003112851
VERSION     WP_003112851.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF015863.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF03929.21
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..850
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..850
                     /product="PepSY domain-containing protein"
                     /calculated_mol_wt=94129
     Region          1..364
                     /region_name="PiuB"
                     /note="PepSY-associated TM region [Function unknown];
                     COG3182"
                     /db_xref="CDD:442415"
     Region          393..520
                     /region_name="Flavodoxin_1"
                     /note="pfam00258"
                     /db_xref="CDD:425562"
     Region          547..850
                     /region_name="SiR_like1"
                     /note="Cytochrome p450- like alpha subunits of E. coli
                     sulfite reductase (SiR) multimerize with beta subunits to
                     catalyze the NADPH dependent reduction of sulfite to
                     sulfide. Beta subunits have an Fe4S4 cluster and a
                     siroheme, while the alpha subunits (cysJ...; cd06200"
                     /db_xref="CDD:99797"
     Site            order(584,654..657,670,672,682..685)
                     /site_type="other"
                     /note="FAD binding pocket [chemical binding]"
                     /db_xref="CDD:99797"
     Site            order(654,656..657)
                     /site_type="other"
                     /note="FAD binding motif [chemical binding]"
                     /db_xref="CDD:99797"
     Site            order(657,813,848,850)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:99797"
     Site            order(672..675,722,724,750..751,780..781,788,790,819)
                     /site_type="other"
                     /note="NAD binding pocket [chemical binding]"
                     /db_xref="CDD:99797"
     Site            order(682,685,688)
                     /site_type="other"
                     /note="phosphate binding motif [ion binding]"
                     /db_xref="CDD:99797"
     Site            order(719,723..726,728)
                     /site_type="other"
                     /note="beta-alpha-beta structure motif"
                     /db_xref="CDD:99797"
ORIGIN      
        1 mkkvwfqlhw ffgisaglvl almgvtgatl sfqdelmral npdvlvvqkr pegvlpldel
       61 vrriegaepg rkvafvwvem dsdkagrify tpppgqrrge srwidpytga fvgeprgegf
      121 fnlmmqlhrf lamgeygkqv taactlilif fclsglylrw prkvfdwraw ltldwsrkgr
      181 sfnwdlhava gtwclalyll aaltglywsy ewyrnglfkl lddapagqqa qrgkpggrge
      241 rpadaaplvv dyaavwnsir qaggdrlqay nlrlppaggq patvfyrltd apherafntl
      301 tldpangqvk sdqrysdrsf gsqllasvya lhvgsyfgma grilmmlasl amplffitgw
      361 llyldrrrkk ravrasradl ggsagasgep wligyasqsg faeqlawqsa gqlqaaglpv
      421 rveslarlda gqlaearkal fvvstfgdge apdsargfer kvlgqaasld glsyallalg
      481 drqyeqfcgf arrmqgwlqg qgarslfapv evddgdaaal rqwqeslaev tggaapaawe
      541 apafevwsla rreclnpgsq gestwlldlr apansaiqwr agdlleivph qapvrirewl
      601 qrhnldgqar vavegveqsl eqalagrllp dsfehlvglh pqalldalip lsvrqysias
      661 lqsdgdlqli vrqeqhadgs lgicsgwlte ylplgaaltl rlrrnagfhl peddvplili
      721 gngtglaglr sllrasiaag rkrnwllfge rnfahdyycr aeleqalarg elqrldlafs
      781 rdqaekiyvq drlheaadel rrwidegaal yvcgslqgma ggvdrvlrev lgeealqrla
      841 degryrrdvy