MULTISPECIES: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

LOCUS       WP_003112824             314 aa            linear   BCT 22-AUG-2022
            [Pseudomonas].
ACCESSION   WP_003112824
VERSION     WP_003112824.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF002188.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK01045
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..314
                     /gene="ispH"
                     /gene_synonym="lytB"
     Protein         1..314
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /GO_process="GO:0050992 - dimethylallyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=34631
     Region          1..302
                     /region_name="ispH"
                     /note="4-hydroxy-3-methylbut-2-enyl diphosphate reductase;
                     Reviewed; PRK01045"
                     /db_xref="CDD:234893"
     Site            order(12,96,198)
                     /site_type="other"
                     /note="Fe-S cluster binding site [ion binding]"
                     /db_xref="CDD:260116"
     Site            order(15,40..41,73..74,124,126,168..169,225..228,270)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:260116"
     Site            order(124,126,226,228)
                     /site_type="active"
                     /note="catalytic site [active]"
                     /db_xref="CDD:260116"
ORIGIN      
        1 mqiklanprg fcagvdraie ivnraldvfg ppiyvrhevv hnkfvvdnlr qrgaifveel
       61 dqvpnnvivi fsahgvsqav rkeaegrglk vfdatcplvt kvhmevvrys rdghecvlig
      121 heghpevegt mgqydasngg aiylvedead vaalevrkpe alhyvtqttl smddtskvid
      181 alrakfpqiq gprkndicya tqnrqdavke ladqcdmvlv vgspnssnsn rlrelaermg
      241 tpaylidgae dmqrgwfdgv rrigitagas apevlvrgvi aqlrewgase eqelegreen
      301 itfsmpkelr vkal