efflux RND transporter periplasmic adaptor subunit [Pseudomonas

LOCUS       WP_003112807             425 aa            linear   BCT 20-JUL-2024
            aeruginosa].
ACCESSION   WP_003112807
VERSION     WP_003112807.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 425)
  AUTHORS   Colclough,A.L., Alav,I., Whittle,E.E., Pugh,H.L., Darby,E.M.,
            Legood,S.W., McNeil,H.E. and Blair,J.M.
  TITLE     RND efflux pumps in Gram-negative bacteria; regulation, structure
            and role in antibiotic resistance
  JOURNAL   Future Microbiol 15, 143-157 (2020)
   PUBMED   32073314
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11436533
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..425
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..425
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0042802 - identical protein binding
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=45834
     Region          47..415
                     /region_name="AcrA"
                     /note="Multidrug efflux pump subunit AcrA (membrane-fusion
                     protein) [Cell wall/membrane/envelope biogenesis, Defense
                     mechanisms]; COG0845"
                     /db_xref="CDD:440606"
ORIGIN      
        1 mttdrfsflr rpalplavgl avvaalawlv faggtakrte gerwvavraa plvhqiglvg
       61 rlepgrvvtl aapfagnvea llvepgqrva egqellrmdt reiavqvrea qsallkarrt
      121 lqdlrdwerg edmarvrral rsaqlaqsst erklretrel fqrgivprne lddleqqasq
      181 qrmdleaarr evestrakgq genrqiaemd lanasvkyet lqaqldgrtv rapfagivva
      241 apglageqgs repvqagskl gqgqalfgla sverlkvsak vseldinqlr egqaveisgd
      301 gfegttlagv iaalggqalp gmaqggspqf evtvsvapld prqlqkirlg msakltvtty
      361 rneqaivvpp eairhegdrl fvdfrqapga svmaqqvkig sstpegvevf elqpglvrvp
      421 sssdr