MULTISPECIES: Re/Si-specific NAD(P)(+) transhydrogenase subunit

LOCUS       WP_003112662             372 aa            linear   BCT 07-JUL-2024
            alpha [Pseudomonas].
ACCESSION   WP_003112662
VERSION     WP_003112662.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 372)
  AUTHORS   Ahmad,S., Glavas,N.A. and Bragg,P.D.
  TITLE     A mutation at Gly314 of the beta subunit of the Escherichia coli
            pyridine nucleotide transhydrogenase abolishes activity and affects
            the NADP(H)-induced conformational change
  JOURNAL   Eur J Biochem 207 (2), 733-739 (1992)
   PUBMED   1633824
REFERENCE   2  (residues 1 to 372)
  AUTHORS   Tong,R.C., Glavas,N.A. and Bragg,P.D.
  TITLE     Topological analysis of the pyridine nucleotide transhydrogenase of
            Escherichia coli using proteolytic enzymes
  JOURNAL   Biochim Biophys Acta 1080 (1), 19-28 (1991)
   PUBMED   1932078
REFERENCE   3  (residues 1 to 372)
  AUTHORS   Clarke,D.M., Loo,T.W., Gillam,S. and Bragg,P.D.
  TITLE     Nucleotide sequence of the pntA and pntB genes encoding the
            pyridine nucleotide transhydrogenase of Escherichia coli
  JOURNAL   Eur J Biochem 158 (3), 647-653 (1986)
   PUBMED   3525165
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF006942.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK09424
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..372
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit alpha"
                     /EC_number="7.1.1.1"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=38551
     Region          1..365
                     /region_name="Rubrum_tdh"
                     /note="Rubrum transdehydrogenase NAD-binding and catalytic
                     domains; cd05304"
                     /db_xref="CDD:240629"
     Site            order(15,73,92,291,317,319)
                     /site_type="other"
                     /note="ligand binding site [chemical binding]"
                     /db_xref="CDD:240629"
     Site            order(44,124..125,134..135,138..139,142..143,145..146,
                     148..153,155,157..159,162,185..186,281..282,324..325,329,
                     332..333)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:240629"
     Site            order(119..120,124,127,130,171..174,194..196,231,242,
                     259..261,268,270)
                     /site_type="other"
                     /note="NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:240629"
     Site            order(121..122,124,134,177..178,185,201..202,204..207)
                     /site_type="other"
                     /note="trimer interface B [polypeptide binding]"
                     /db_xref="CDD:240629"
     Site            order(154..158,161,164,187,189)
                     /site_type="other"
                     /note="trimer interface A [polypeptide binding]"
                     /db_xref="CDD:240629"
ORIGIN      
        1 mqigvpleth agetrvsatp etvkkligqg hqvivqsgag vsasqpdsay eaagatigsa
       61 aeafgadlvl kvvapsaael aqmksgavlv gmlnpfdnen iarmaergit afaleaaprt
      121 sraqsldvls sqaniagyka vmlaanhypr fmpmlmtaag tvkaarvlil gagvaglqai
      181 atakrlgavi easdvrpavk eqieslgakf vdvpyetdee recaegvggy arpmpaswme
      241 rqakavhera kqsdivitta lipgrkaptl lheatvaemk pgsvvidlaa aqggncplte
      301 adqvvvrhgv tivghsnlaa lvpadasaly arnildflkl tlnaegfsvn leddivaacl
      361 mcrdgqavrk ng