MULTISPECIES: arsenate reductase (glutaredoxin) [Pseudomonas].

LOCUS       WP_003112580             117 aa            linear   BCT 04-MAR-2024
ACCESSION   WP_003112580
VERSION     WP_003112580.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 117)
  AUTHORS   Liu,J., Gladysheva,T.B., Lee,L. and Rosen,B.P.
  TITLE     Identification of an essential cysteinyl residue in the ArsC
            arsenate reductase of plasmid R773
  JOURNAL   Biochemistry 34 (41), 13472-13476 (1995)
   PUBMED   7577935
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00014.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..117
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..117
                     /gene="arsC"
     Protein         1..117
                     /product="arsenate reductase (glutaredoxin)"
                     /EC_number="1.20.4.1"
                     /GO_function="GO:0008794 - arsenate reductase
                     (glutaredoxin) activity [Evidence IEA]"
                     /GO_process="GO:0046685 - response to arsenic-containing
                     substance [Evidence IEA]"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance.;
                     This arsenate reductase requires both glutathione and
                     glutaredoxin to convert arsenate to arsenite, after which
                     the efflux transporter formed by ArsA and ArsB can extrude
                     the arsenite from the cell, providing resistance."
                     /calculated_mol_wt=12659
     Region          6..115
                     /region_name="ArsC_ArsC"
                     /note="Arsenate Reductase (ArsC) family, ArsC subfamily;
                     arsenic reductases similar to that encoded by arsC on the
                     R733 plasmid of Escherichia coli. E. coli ArsC catalyzes
                     the reduction of arsenate [As(V)] to arsenite [As(III)],
                     the first step in the...; cd03034"
                     /db_xref="CDD:239332"
     Site            order(12,60,94,107)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239332"
ORIGIN      
        1 mselillhnp rcsksraale llearglqpq vvryletpps aaelkailak lgiparqllr
       61 tgedeykalg ldepslgeea iieamarhpk lierpvlvag dkavvgrppe rvleila