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MULTISPECIES: anthranilate--CoA ligase [Pseudomonas].


LOCUS       WP_003112552             517 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_003112552
VERSION     WP_003112552.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 517)
  AUTHORS   Coleman,J.P., Hudson,L.L., McKnight,S.L., Farrow,J.M. 3rd,
            Calfee,M.W., Lindsey,C.A. and Pesci,E.C.
  TITLE     Pseudomonas aeruginosa PqsA is an anthranilate-coenzyme A ligase
  JOURNAL   J Bacteriol 190 (4), 1247-1255 (2008)
   PUBMED   18083812
REFERENCE   2  (residues 1 to 517)
  AUTHORS   Lepine,F., Dekimpe,V., Lesic,B., Milot,S., Lesimple,A., Mamer,O.A.,
            Rahme,L.G. and Deziel,E.
  TITLE     PqsA is required for the biosynthesis of 2,4-dihydroxyquinoline
            (DHQ), a newly identified metabolite produced by Pseudomonas
            aeruginosa and Burkholderia thailandensis
  JOURNAL   Biol Chem 388 (8), 839-845 (2007)
   PUBMED   17655503
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR013469
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..517
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..517
                     /gene="pqsA"
     Protein         1..517
                     /product="anthranilate--CoA ligase"
                     /EC_number="6.2.1.32"
                     /calculated_mol_wt=56477
     Region          19..500
                     /region_name="BCL_like"
                     /note="Benzoate CoA ligase (BCL) and similar adenylate
                     forming enzymes; cd05919"
                     /db_xref="CDD:341243"
     Site            order(50,52,54..55,100,109..110,355..356,358,363..366,370,
                     374..376)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:341243"
     Site            order(161,164..169,171..172)
                     /site_type="other"
                     /note="acyl-activating enzyme (AAE) consensus motif"
                     /db_xref="CDD:341243"
     Site            order(164,205..206,209..211,254,256..257,260,278..279,
                     299..304,308..309,382,394,397,405..408,474,493)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:341243"
     Site            order(164,278..279,299..304,382,394,397,408,493)
                     /site_type="other"
                     /note="putative AMP binding site [chemical binding]"
                     /db_xref="CDD:341243"
     Site            order(205,256..257,260,278,405..407,468,474)
                     /site_type="other"
                     /note="putative CoA binding site [chemical binding]"
                     /db_xref="CDD:341243"
     Site            order(209..211,278..279,302..304,308..309,493)
                     /site_type="other"
                     /note="chemical substrate binding site [chemical binding]"
                     /db_xref="CDD:341243"
ORIGIN      
        1 mstlanltev lfrldfdpdt avyhyrgqtl srlqcrtyil sqasqlarll kpgdrvvlal
       61 ndspslaclf laciavgaip avinpksreq aladiaadcq aslvvreada pslsgplapl
      121 tlraaagrpl lddfsldalv gpadldwsaf hrqdpaaacf lqytsgstga pkgvmhslrn
      181 tlgfcrafat ellalqagdr lysipkmffg ygmgnslffp wfsgasalld dtwpspervl
      241 enlvafrprv lfgvpaiyas lrpqarells svrlafsags plprgefefw aahgleicdg
      301 igatevghvf lanrpgqara dstglplpgy ecrlvdregh tieeagrqgv llvrgpglsp
      361 gywraseeqq arfaggwyrt gdlferdesg ayrhcgredd lfkvngrwvv ptqveqaicr
      421 hlpevseavl vptcrlhdgl rptlfvtlat plddnqilla qridqhlaeq ipshmlpsql
      481 hvlpalprnd ngklaraelr hladtlyhdn lpeerac