exotoxin A [Pseudomonas aeruginosa].

LOCUS       WP_003112478             638 aa            linear   BCT 04-OCT-2019
ACCESSION   WP_003112478
VERSION     WP_003112478.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 638)
  AUTHORS   Michalska,M. and Wolf,P.
  TITLE     Pseudomonas Exotoxin A: optimized by evolution for effective
            killing
  JOURNAL   Front Microbiol 6, 963 (2015)
   PUBMED   26441897
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR009917
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..638
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     gene            1..638
                     /gene="toxA"
     Protein         1..638
                     /product="exotoxin A"
                     /EC_number="2.4.2.36"
                     /calculated_mol_wt=69153
     Region          27..275
                     /region_name="Exotox-A_bind"
                     /note="Exotoxin A binding; pfam09101"
                     /db_xref="CDD:286224"
     Region          277..407
                     /region_name="Exotox-A_target"
                     /note="Exotoxin A, targeting; pfam09102"
                     /db_xref="CDD:401151"
     Region          447..618
                     /region_name="Exotox-A_cataly"
                     /note="Exotoxin A catalytic; pfam09009"
                     /db_xref="CDD:430368"
     Site            order(464..468,471,475,478,480..481,494..496,506,578,583)
                     /site_type="other"
                     /note="nad+ binding pocket [chemical binding]"
                     /db_xref="CDD:238716"
ORIGIN      
        1 mhltphwipl vaslgllagg sfasaaeeaf dlwnecakac vldlkdgvrs srmsvdpaia
       61 dtngqgvlhy smvleggnda lklaidnals itsdgltirl eggvepnkpv rysytrqarg
      121 swslnwlvpi ghekpsnikv fihelnagnq lshmspiyti emgdellakl ardatffvra
      181 hesnemqptl aishagvsvv maqaqprrek rwsewasgkv lclldpldgv ynylaqqrcn
      241 lddtwegkiy rvlagnpakh dldikptvis hrlhfpeggs laaltahqac hlpletftrh
      301 rqprgweqle qcgypvqrlv alylaarlsw nqvdqvirna laspgsggdl geaireqpeq
      361 arlaltlaaa eserfvrqgt gndeagaasa dvvsltcpva agecagpads gdallernyp
      421 tgaeflgdgg disfstrgtq nwtverllqa hrqleergyv fvgyhgtfle aaqsivfggv
      481 rarsqdldai wrgfyiagdp alaygyaqdq epdargrirn gallrvyvpr sslpgfyrtg
      541 ltlaapeaag everlighpl plrldaitgp eeeggrleti lgwplaertv vipsaiptdp
      601 rnvggdldps sipdkeqais alpdyasqpg kppredlk