cyclic di-GMP receptor LapD [Pseudomonas aeruginosa].

LOCUS       WP_003112436             650 aa            linear   BCT 11-FEB-2024
ACCESSION   WP_003112436
VERSION     WP_003112436.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 650)
  AUTHORS   Chatterjee,D., Cooley,R.B., Boyd,C.D., Mehl,R.A., O'Toole,G.A. and
            Sondermann,H.
  TITLE     Mechanistic insight into the conserved allosteric regulation of
            periplasmic proteolysis by the signaling molecule cyclic-di-GMP
  JOURNAL   Elife 3, e03650 (2014)
   PUBMED   25182848
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 650)
  AUTHORS   Hinsa,S.M. and O'Toole,G.A.
  TITLE     Biofilm formation by Pseudomonas fluorescens WCS365: a role for
            LapD
  JOURNAL   Microbiology (Reading) 152 (Pt 5), 1375-1383 (2006)
   PUBMED   16622054
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF045673.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..650
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     gene            1..650
                     /gene="lapD"
     Protein         1..650
                     /product="cyclic di-GMP receptor LapD"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /calculated_mol_wt=71845
     Region          23..145
                     /region_name="LapD_MoxY_N"
                     /note="LapD/MoxY periplasmic domain; pfam16448"
                     /db_xref="CDD:465117"
     Region          90..645
                     /region_name="EAL"
                     /note="EAL domain, c-di-GMP-specific phosphodiesterase
                     class I (or its enzymatically inactive variant) [Signal
                     transduction mechanisms]; COG2200"
                     /db_xref="CDD:441802"
ORIGIN      
        1 msllkqlfla iclflvvafs gsfvssvens reqlrgqlrs haqdaatalg lsltphvddp
       61 amvqlmvssi fdsgyfasir vidiksgkpl vervqahaer tvpgwferlv dlqpqggdal
      121 imrgweqaar vevvshpqfa larlwdsalg slywllacga aslllggwll rrqlrpldqm
      181 vrqahaisrr eflslprlpr tpelrrvvqa mnqmveklrt lfaeeaarsd klraqayqds
      241 ltglpnrrlf darlneqlga gehehagqll llrlndlngl nqrlggqrtd eliqavarll
      301 vdscgqqgra dwllarsrgg efavlapgcs reqaerlaee lceglenlar tgasdltpva
      361 ylgisafaeg dspadllara dqalaqaesq paqpwasqdg talaalndsq dwhdwidqal
      421 terrlllyfq pvvdcldtqr vlhhkvlarl ldpqataiaa grflpwierf gwaarmdlam
      481 leqslehlrr hprplalsls aasvrnaqtf apllallkah pqearqltle lderhlpaaa
      541 elerlsqvlr elgcglglqh fggrfslign lthlglaylk ldgcylhavd regdkrlfie
      601 avyrtthsid lpliaeqvet lgelevlrem glrgamgrlf gspapwsgda