mechanosensitive ion channel family protein [Pseudomonas

LOCUS       WP_003112423             807 aa            linear   BCT 01-JAN-2025
            aeruginosa].
ACCESSION   WP_003112423
VERSION     WP_003112423.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 807)
  AUTHORS   Cox,C.D., Nakayama,Y., Nomura,T. and Martinac,B.
  TITLE     The evolutionary 'tinkering' of MscS-like channels: generation of
            structural and functional diversity
  JOURNAL   Pflugers Arch 467 (1), 3-13 (2015)
   PUBMED   24819593
REFERENCE   2  (residues 1 to 807)
  AUTHORS   Malcolm,H.R. and Maurer,J.A.
  TITLE     The mechanosensitive channel of small conductance (MscS)
            superfamily: not just mechanosensitive channels anymore
  JOURNAL   Chembiochem 13 (14), 2037-2043 (2012)
   PUBMED   22915507
REFERENCE   3  (residues 1 to 807)
  AUTHORS   Haswell,E.S., Phillips,R. and Rees,D.C.
  TITLE     Mechanosensitive channels: what can they do and how do they do it?
  JOURNAL   Structure 19 (10), 1356-1369 (2011)
   PUBMED   22000509
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11461657
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..807
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..807
                     /product="mechanosensitive ion channel family protein"
                     /GO_function="GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /calculated_mol_wt=86256
     Region          <27..446
                     /region_name="PksD"
                     /note="Acyl transferase domain in polyketide synthase
                     (PKS) enzymes [Secondary metabolites biosynthesis,
                     transport and catabolism]; COG3321"
                     /db_xref="CDD:442550"
     Region          140..201
                     /region_name="DUF3772"
                     /note="Protein of unknown function (DUF3772); pfam12607"
                     /db_xref="CDD:432664"
     Region          523..794
                     /region_name="MscK"
                     /note="Small-conductance mechanosensitive channel MscK
                     [Cell wall/membrane/envelope biogenesis]; COG3264"
                     /db_xref="CDD:442495"
ORIGIN      
        1 mrraslhmll cqfamalgll lslgseawaa rpapqaavdl eapaalaeda sldqlnaqld
       61 lirqrvtada sddllaelrq salqvqrqad allalrvadi erlddqlkvi gppqpdeaes
      121 laaqrqaltr qknalldder qatqlgqssr dlaaqivnlr rslfnsqiss raatpfspsf
      181 wstlirptdd dlrrldklka ealvafdsai apghrwafag tllatvlvws fgrrllerml
      241 twamirwlpe grlrrsalal avglatilti vgavslmrwg lesnaslspd masltdqlvs
      301 latfcafiag lgrallmlpr pswrlpaipd riasalgpfp ailavalmlv ateerinnvt
      361 gtslaltval ngltalvtal ifaaallryh hvrrkhdler pggiaglipf vasvwiaail
      421 lalftgylsl ayfltgkllw isviaattyl liaffgdice tllspkhpsg lalanalgls
      481 prhqaqastv lagvgrtlll ltalllaflp vgsspsellq gfaqlgessk tlgnlnivpq
      541 dilvalllfv gglfalrivk rwlserllpe tnmdagmras lvtlvgylgf vllamlvmst
      601 lrinltsltw vvsalsvgig fglqaivqnf isglillter pvkvgdwvsl ggvegdirri
      661 nvrateiqmg drstvivpns qfisqtvrnv tmgnalgvvg vnltlpldtd amkvrelllq
      721 afaehpaild apapsvtfkd lasnglvlna sgfvnsprsv agarsdllft ildrlrsegi
      781 alsspqsllm iqdggpasaa papatpd