MFS transporter [Pseudomonas aeruginosa].

LOCUS       WP_003112386             403 aa            linear   BCT 22-JUL-2024
ACCESSION   WP_003112386
VERSION     WP_003112386.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas aeruginosa
  ORGANISM  Pseudomonas aeruginosa
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae; Pseudomonas.
REFERENCE   1  (residues 1 to 403)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 403)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023516
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..403
                     /organism="Pseudomonas aeruginosa"
                     /db_xref="taxon:287"
     Protein         1..403
                     /product="MFS transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=40645
     Region          13..386
                     /region_name="MFS_NepI_like"
                     /note="Purine ribonucleoside efflux pump NepI and similar
                     transporters of the Major Facilitator Superfamily;
                     cd17324"
                     /db_xref="CDD:340882"
     Site            order(23..24,27..28,31,63,113..114,116..118,121,141,
                     144..145,148,222,225..226,229..231,234,262,266,316..317,
                     321,325,340,343..344,347..348,351)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340882"
ORIGIN      
        1 mpsspsslps alvllfavac glsvanvyya qplldvlgae faigqagvgl lfgttqagca
       61 lalllvvplg dllerrrlmf vqllllvlsl llvgfagdtl glalgllglg llgtamtqgl
      121 layaaalaap gergrvvgaa qggvviglll arslagllad lggwrsvylv saasmgglgl
      181 llwrvlpaap snelgltyrq llgsmfdlla sqrvlqvrgl lgllmfaafg vfwsslvlll
      241 gapphslshs aigafglvga lgalgaarag sladrghaqa lsggalllll lswlplalga
      301 hslaalilgv llldlagqai hvlnqslvfa idprahsrlv gcymlfyaag sglgasagta
      361 myawagwdav sllgaaisla alafwwftrg vggeartaca nga