MULTISPECIES: MFS transporter [Pseudomonas].

LOCUS       WP_003112299             446 aa            linear   BCT 24-DEC-2024
ACCESSION   WP_003112299
VERSION     WP_003112299.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 446)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 446)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 446)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
REFERENCE   4  (residues 1 to 446)
  AUTHORS   Yan,N.
  TITLE     Structural advances for the major facilitator superfamily (MFS)
            transporters
  JOURNAL   Trends Biochem Sci 38 (3), 151-159 (2013)
   PUBMED   23403214
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024277
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..446
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..446
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=46647
     Region          23..430
                     /region_name="MFS_PcaK_like"
                     /note="4-hydroxybenzoate transporter PcaK and similar
                     transporters of the Major Facilitator Superfamily;
                     cd17365"
                     /db_xref="CDD:340923"
     Site            order(33..34,37..38,41,73,123..124,126..128,131,151,
                     154..155,158,260,263..264,267..269,272,299,303,352..353,
                     357,361,377,380..381,384..385,388)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340923"
ORIGIN      
        1 mnrqsaaavi daarfnrthw lilgwgcfim lfdgydmviy gsvvprlmqe wqlspvqagt
       61 lgscalfgml fggtllapla drfgrrrlvi attllaslaa fltghardpl elgagrfftg
      121 lalgalvpsa inlisefapa grrstlvtvm safysvgavl sallaiamip awgwqsvfyv
      181 avlpvlavpl mlrwlpesaa flelkgrrae ldallrkvdp dyrpgaeran avaaeapsgr
      241 vaqlfegrqa vgtlllwvaf amcmlmsygl ntwlpklmag ggyalgssla flvtlnvgat
      301 lgalfggwla drlgagrtlv lffalaaasl aalglgpgpw llngllvvag attigtlavi
      361 hayaaqfypa wvrstgvgwa agvgrlgaia gpmlggslla lelpfqqnfl afaapgviga
      421 laiacihlrp rvpaeasvda takkpl