MULTISPECIES: SDR family oxidoreductase [Pseudomonas].

LOCUS       WP_003111019             303 aa            linear   BCT 27-JUL-2024
ACCESSION   WP_003111019
VERSION     WP_003111019.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 303)
  AUTHORS   Kavanagh,K.L., Jornvall,H., Persson,B. and Oppermann,U.
  TITLE     Medium- and short-chain dehydrogenase/reductase gene and protein
            families : the SDR superfamily: functional and structural diversity
            within a family of metabolic and regulatory enzymes
  JOURNAL   Cell Mol Life Sci 65 (24), 3895-3906 (2008)
   PUBMED   19011750
REFERENCE   2  (residues 1 to 303)
  AUTHORS   Oppermann,U., Filling,C., Hult,M., Shafqat,N., Wu,X., Lindh,M.,
            Shafqat,J., Nordling,E., Kallberg,Y., Persson,B. and Jornvall,H.
  TITLE     Short-chain dehydrogenases/reductases (SDR): the 2002 update
  JOURNAL   Chem Biol Interact 143-144, 247-253 (2003)
   PUBMED   12604210
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10143226
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..303
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..303
                     /product="SDR family oxidoreductase"
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /calculated_mol_wt=32192
     Region          5..254
                     /region_name="hydroxyacyl-CoA-like_DH_SDR_c-like"
                     /note="(3R)-hydroxyacyl-CoA dehydrogenase-like,
                     classical(c)-like SDRs; cd05353"
                     /db_xref="CDD:187611"
     Site            order(5,32,107..109,111..113,116..117,120,124..125,128,
                     131..132,135..136,152..160,162,165..166,169..170,172..174,
                     176..178,180..181,183..184,186,209,212..213,217,220..221,
                     223..225,232,236..238,240..254)
                     /site_type="other"
                     /note="homodimer interface [polypeptide binding]"
                     /db_xref="CDD:187611"
     Site            order(16,19..21,39..41,43,75..76,99..102,122..123,
                     149..151,164,168,194..196,198..201)
                     /site_type="other"
                     /note="NAD binding site [chemical binding]"
                     /db_xref="CDD:187611"
     Site            order(123,151,164,168)
                     /site_type="active"
                     /db_xref="CDD:187611"
ORIGIN      
        1 msdalrfddq vvivtgaggg lgrahallfa khgarvvvnd lggsthgega sasaadkvva
       61 eiraaggtav anhdsvtdgg rivenaldaf grvdvvvnna gilrdktfhk medadwdlvy
      121 qvhvegaykv traawphlre qaygrvvfts stsgiygnfg qsnygmaklg lygltrtlal
      181 egrknnilvn aiaptggtrm teglippqvf eqlkpelvsp lvvylgssac edtsglyevg
      241 ggwigkvrwe rslgfgfdpk agfdaedvaa hwqqicdfen aahpadnvea lremmanlqk
      301 hal