MULTISPECIES: GDP-mannose 6-dehydrogenase [Pseudomonas].

LOCUS       WP_003110461             436 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_003110461
VERSION     WP_003110461.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 436)
  AUTHORS   Chen,L., Yang,J., Yu,J., Yao,Z., Sun,L., Shen,Y. and Jin,Q.
  TITLE     VFDB: a reference database for bacterial virulence factors
  JOURNAL   Nucleic Acids Res 33 (Database issue), D325-D328 (2005)
   PUBMED   15608208
REFERENCE   2  (residues 1 to 436)
  AUTHORS   Snook,C.F., Tipton,P.A. and Beamer,L.J.
  TITLE     Crystal structure of GDP-mannose dehydrogenase: a key enzyme of
            alginate biosynthesis in P. aeruginosa
  JOURNAL   Biochemistry 42 (16), 4658-4668 (2003)
   PUBMED   12705829
REFERENCE   3  (residues 1 to 436)
  AUTHORS   Naught,L.E., Gilbert,S., Imhoff,R., Snook,C., Beamer,L. and
            Tipton,P.
  TITLE     Allosterism and cooperativity in Pseudomonas aeruginosa GDP-mannose
            dehydrogenase
  JOURNAL   Biochemistry 41 (30), 9637-9645 (2002)
   PUBMED   12135385
REFERENCE   4  (residues 1 to 436)
  AUTHORS   Maharaj,R., May,T.B., Wang,S.K. and Chakrabarty,A.M.
  TITLE     Sequence of the alg8 and alg44 genes involved in the synthesis of
            alginate by Pseudomonas aeruginosa
  JOURNAL   Gene 136 (1-2), 267-269 (1993)
   PUBMED   8294014
REFERENCE   5  (residues 1 to 436)
  AUTHORS   Roychoudhury,S., Chakrabarty,K., Ho,Y.K. and Chakrabarty,A.M.
  TITLE     Characterization of guanosine diphospho-D-mannose dehydrogenase
            from Pseudomonas aeruginosa. Structural analysis by limited
            proteolysis
  JOURNAL   J Biol Chem 267 (2), 990-996 (1992)
   PUBMED   1370473
REFERENCE   6  (residues 1 to 436)
  AUTHORS   Roychoudhury,S., May,T.B., Gill,J.F., Singh,S.K., Feingold,D.S. and
            Chakrabarty,A.M.
  TITLE     Purification and characterization of guanosine diphospho-D-mannose
            dehydrogenase. A key enzyme in the biosynthesis of alginate by
            Pseudomonas aeruginosa
  JOURNAL   J Biol Chem 264 (16), 9380-9385 (1989)
   PUBMED   2470755
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR012388
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..436
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..436
                     /gene="algD"
     Protein         1..436
                     /product="GDP-mannose 6-dehydrogenase"
                     /EC_number="1.1.1.132"
                     /calculated_mol_wt=47469
     Region          1..420
                     /region_name="NDP-sugDHase"
                     /note="nucleotide sugar dehydrogenase; TIGR03026"
                     /db_xref="CDD:274399"
ORIGIN      
        1 mrisifglgy vgavcagcls arghevigvd vsstkidlin qgkspivepg leallqqgrq
       61 tgrlsgttdf kkavldsdvs ficvgtpskk ngdldlgyie tvcreigfai rekserhtvv
      121 vrstvlpgtv nnvviplied csgkkagvdf gvgtnpeflr estaikdydf ppmtvigeld
      181 kqtgdlleei yreldapiir ktvevaemik ytcnvwhaak vtfaneigni akavgvdgre
      241 vmdvicqdhk lnlsryymrp gfafggsclp kdvraltyra sqldvehpml gslmrsnsnq
      301 vqkafdlits hdtrkvgllg lsfkagtddl resplvelae mligkgyelr ifdrnveyar
      361 vhgankeyie skiphvssll vsdldevvas sdvlvlgngd elfvdlvnkt psgkklvdlv
      421 gfmphtttaq aegicw