MULTISPECIES: multiple virulence factor transcriptional regulator

LOCUS       WP_003108614             332 aa            linear   BCT 20-NOV-2023
            MvfR [Pseudomonas].
ACCESSION   WP_003108614
VERSION     WP_003108614.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 332)
  AUTHORS   Kitao,T., Lepine,F., Babloudi,S., Walte,F., Steinbacher,S.,
            Maskos,K., Blaesse,M., Negri,M., Pucci,M., Zahler,B., Felici,A. and
            Rahme,L.G.
  TITLE     Molecular Insights into Function and Competitive Inhibition of
            Pseudomonas aeruginosa Multiple Virulence Factor Regulator
  JOURNAL   mBio 9 (1), e02158-17 (2018)
   PUBMED   29339431
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 332)
  AUTHORS   Maura,D. and Rahme,L.G.
  TITLE     Pharmacological Inhibition of the Pseudomonas aeruginosa MvfR
            Quorum-Sensing System Interferes with Biofilm Formation and
            Potentiates Antibiotic-Mediated Biofilm Disruption
  JOURNAL   Antimicrob Agents Chemother 61 (12), e01362-17 (2017)
   PUBMED   28923875
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 332)
  AUTHORS   Maura,D., Hazan,R., Kitao,T., Ballok,A.E. and Rahme,L.G.
  TITLE     Evidence for Direct Control of Virulence and Defense Gene Circuits
            by the Pseudomonas aeruginosa Quorum Sensing Regulator, MvfR
  JOURNAL   Sci Rep 6, 34083 (2016)
   PUBMED   27678057
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 332)
  AUTHORS   Xiao,G., Deziel,E., He,J., Lepine,F., Lesic,B., Castonguay,M.H.,
            Milot,S., Tampakaki,A.P., Stachel,S.E. and Rahme,L.G.
  TITLE     MvfR, a key Pseudomonas aeruginosa pathogenicity LTTR-class
            regulatory protein, has dual ligands
  JOURNAL   Mol Microbiol 62 (6), 1689-1699 (2006)
   PUBMED   17083468
REFERENCE   5  (residues 1 to 332)
  AUTHORS   Cao,H., Krishnan,G., Goumnerov,B., Tsongalis,J., Tompkins,R. and
            Rahme,L.G.
  TITLE     A quorum sensing-associated virulence gene of Pseudomonas
            aeruginosa encodes a LysR-like transcription regulator with a
            unique self-regulatory mechanism
  JOURNAL   Proc Natl Acad Sci U S A 98 (25), 14613-14618 (2001)
   PUBMED   11724939
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR013252
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..332
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..332
                     /gene="mvfR"
     Protein         1..332
                     /product="multiple virulence factor transcriptional
                     regulator MvfR"
                     /calculated_mol_wt=37083
     Region          5..294
                     /region_name="LysR"
                     /note="DNA-binding transcriptional regulator, LysR family
                     [Transcription]; COG0583"
                     /db_xref="CDD:440348"
ORIGIN      
        1 mpihnlnhvn mflqviasgs issaarilrk shtavssavs nleidlcvel vrrdgykvep
       61 teqalrlipy mrsllnyqql igdiafnlnk gprnlrvlld taippsfcdt vssvllddfn
      121 mvslirtspa dslatikqdn aeidiaitid eelkisrfnq cvlgytkafv vahpqhplcn
      181 aslhsiasla nyrqislgsr sgqhsnllrp vsdkvlfven fddmlrlvea gvgwgiaphy
      241 fveerlrngt lavlselyep ggidtkvycy yntalesers flrflesarq rlrelgrqrf
      301 ddapawqpsi vetaqrrsgp kalayrqraa pe