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LOCUS WP_003106336 245 aa linear BCT 20-NOV-2023 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase [Pseudomonas]. ACCESSION WP_003106336 VERSION WP_003106336.1 KEYWORDS RefSeq. SOURCE Pseudomonas ORGANISM Pseudomonas Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae. REFERENCE 1 (residues 1 to 245) AUTHORS Barona-Gomez,F. and Hodgson,D.A. TITLE Occurrence of a putative ancient-like isomerase involved in histidine and tryptophan biosynthesis JOURNAL EMBO Rep. 4 (3), 296-300 (2003) PUBMED 12634849 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: HMM Evidence Accession :: TIGR00007.1 Evidence Source :: JCVI ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..245 /organism="Pseudomonas" /db_xref="taxon:286" gene 1..245 /gene="hisA" Protein 1..245 /product="1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase" /EC_number="5.3.1.16" /GO_function="GO:0003949 - 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase activity [Evidence IEA]" /GO_process="GO:0000105 - histidine biosynthetic process [Evidence IEA]" /calculated_mol_wt=25807 Region 1..236 /region_name="PRK00748" /note="1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Validated" /db_xref="CDD:179108" Site order(8,48,130) /site_type="active" /note="catalytic residues [active]" /db_xref="CDD:240083" ORIGIN 1 mliipaidlk dgacvrlrqg lmedatvfsd dpvamaakwv dggcrrlhlv dlngafegkp 61 vngevvtaia rrypdlpiqi gggirsleti ehyvragvsy viigtkavkq pefvgeacra 121 fpgkvivgld akdgfvatdg waevsevqvi dlarrfeadg vsaivytdis kdgmmqgcnv 181 eataalanat ripviasggi hnlgdiqkll dartpgiiga itgraiyegt ldvaeaqalc 241 dnfka