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MULTISPECIES: MFS transporter [Pseudomonas].


LOCUS       WP_003106293             539 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_003106293
VERSION     WP_003106293.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 539)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 539)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 539)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024289
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..539
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..539
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=58238
     Region          21..527
                     /region_name="MFS_ShiA_like"
                     /note="Shikimate transporter and similar proteins of the
                     Major Facilitator Superfamily; cd17369"
                     /db_xref="CDD:340927"
     Site            order(34..35,38..39,42,80,138..139,141..143,146,166,
                     169..170,173,258,261..262,265..267,270,298,302,453..454,
                     458,462,478,481..482,485..486,489)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340927"
ORIGIN      
        1 mteyattpsy tvpattpqee rkvifasslg tvfewydffl ygalaavisk qffagvndtt
       61 afifalmafa agflvrpfga lvfgrlgdmi grkytflvti llmglstfav gllptyasig
      121 vaapiilvtl rmlqglalgg eyggaaiyva ehapankrgs ytswiqstat lglllsllvi
      181 lacrqltgde fetwgwrlpf llsivllgis twirlsmres paflkmkaeg kvskaplres
      241 ftqwgnlkvv ltalfsinag qavtfytaqf yvlffltqvl kvdggtangl livalvlgap
      301 ffivagwlsd rigrkpvlla glllatlfyf plfkglthya npaidqasrq spisvvadpa
      361 tctfqfdpvg katfdspcdk vktflvkagl pystvaapag sdvrvriget eiagfdaeam
      421 aaavktagyp qqadgsqvnk pmviaiifal vlistlcygp laalmvelfp trirysslsl
      481 pyhigngwfg gflptvsfal vvytgdifyg lwypvlitgg slvcallflr etrhtdihr