MULTISPECIES: NADP-dependent succinate-semialdehyde dehydrogenase

LOCUS       WP_003106269             483 aa            linear   BCT 20-NOV-2023
            [Pseudomonas].
ACCESSION   WP_003106269
VERSION     WP_003106269.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008415.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11241
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..483
                     /gene="gabD"
     Protein         1..483
                     /product="NADP-dependent succinate-semialdehyde
                     dehydrogenase"
                     /GO_function="GO:0009013 - succinate-semialdehyde
                     dehydrogenase [NAD(P)+] activity [Evidence IEA]"
                     /GO_process="GO:0009450 - gamma-aminobutyric acid
                     catabolic process [Evidence IEA]"
                     /calculated_mol_wt=51491
     Region          1..481
                     /region_name="gabD"
                     /note="NADP-dependent succinate-semialdehyde dehydrogenase
                     I; PRK11241"
                     /db_xref="CDD:183050"
     Site            order(68,77,118,121..122,124..132,138..140,145,227,239,
                     243,246,303,307,353,421,423..424,428,430,433,435..441,447,
                     450..451,457,462,474..480)
                     /site_type="other"
                     /note="tetramerization interface [polypeptide binding]"
                     /db_xref="CDD:143421"
     Site            order(153..157,165,180,182..183,231..234,237,240..241,
                     255..257,289,386,388,414,452)
                     /site_type="other"
                     /note="NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:143421"
     Site            order(157,255,286,289)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:143421"
ORIGIN      
        1 mqlkdaklfr qqayvdgawv dadngqtikv nnpatgeiig svpkmgaaet rraieaadka
       61 lpawraltak eranklrrwf dlmienqddl arlmtieqgk plaeakgeia yaasflewfg
      121 eeakriygdt ipghqpdkri ivikqpigvt aaitpwnfps amitrkagpa laagctmvlk
      181 pasqtpysal alaelaerag ipkgvfsvvt gsagevggel tsnpivrklt ftgsteigrq
      241 lmaecaqdik kvslelggna pfivfddadl daavegalis kyrnngqtcv canrlyvqdg
      301 vydafvdklk aavaklnign gleagvttgp lidakavakv eehiadavsk gakvvsggkp
      361 halggtffep tilvdvpkna lvskdetfgp lapvfrfkde aeviamsndt efglasyfya
      421 rdlarvfrva eqleygmvgi ntglisneva pfggikasgl gregskygie dyleikylcl
      481 ggi