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MULTISPECIES: diguanylate cyclase GcbA [Pseudomonas].


LOCUS       WP_003106227             542 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_003106227
VERSION     WP_003106227.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 542)
  AUTHORS   Xiao,Y., Nie,H., Liu,H., Chen,W. and Huang,Q.
  TITLE     Expression of the diguanylate cyclase GcbA is regulated by FleQ in
            response to cyclic di-GMP in Pseudomonas putida KT2440
  JOURNAL   Environ Microbiol Rep 8 (6), 993-1002 (2016)
   PUBMED   27701843
REFERENCE   2  (residues 1 to 542)
  AUTHORS   Petrova,O.E., Cherny,K.E. and Sauer,K.
  TITLE     The Pseudomonas aeruginosa diguanylate cyclase GcbA, a homolog of
            P. fluorescens GcbA, promotes initial attachment to surfaces, but
            not biofilm formation, via regulation of motility
  JOURNAL   J Bacteriol 196 (15), 2827-2841 (2014)
   PUBMED   24891445
REFERENCE   3  (residues 1 to 542)
  AUTHORS   Newell,P.D., Yoshioka,S., Hvorecny,K.L., Monds,R.D. and
            O'Toole,G.A.
  TITLE     Systematic analysis of diguanylate cyclases that promote biofilm
            formation by Pseudomonas fluorescens Pf0-1
  JOURNAL   J Bacteriol 193 (18), 4685-4698 (2011)
   PUBMED   21764921
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR014352
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..542
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..542
                     /gene="gcbA"
     Protein         1..542
                     /product="diguanylate cyclase GcbA"
                     /calculated_mol_wt=61469
     Region          249..527
                     /region_name="PleD"
                     /note="Two-component response regulator, PleD family,
                     consists of two REC domains and a diguanylate cyclase
                     (GGDEF) domain [Signal transduction mechanisms,
                     Transcription]; COG3706"
                     /db_xref="CDD:442920"
     Region          379..534
                     /region_name="GGDEF"
                     /note="Diguanylate-cyclase (DGC) or GGDEF domain; cd01949"
                     /db_xref="CDD:143635"
     Site            order(415,458)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:143635"
     Site            order(420,423..424,428,432,454,456..459)
                     /site_type="active"
                     /db_xref="CDD:143635"
     Site            order(450,478)
                     /site_type="active"
                     /note="I-site [active]"
                     /db_xref="CDD:143635"
ORIGIN      
        1 mmtehddptl drlkhhfaqr vinqarqvle vwqrltraew nsdgmeelad atlrlqryae
       61 rfeqaehaql agaidrtldv veanrgrlss esiselnqlm qrlsrtglrh gdqlehtvlp
      121 plrkpvylal kdreraerla qqleffglqa lscetadafr asmrerypaa ivmevdfagp
      181 dmglrlasea qaglehklpv lffsdsetdt ptrlaaarag gqefftgtld assvlekiet
      241 lsrlsfyepy rvlivddsra qalhtemvln sagiitralt eplsvmaels dfqpdliild
      301 mympeclgte lakvirqher hvsvpiiyls aeddldkqld amseggddfl tkpirprhli
      361 atvrtrasra rslkarmvrd sltglynhth tlqlledarl rarrdgrpls famldidhfk
      421 qvndrfghpm gdrvikglal flkqrlrktd higryggeef avvlpdtdld aarlvldeir
      481 qrfaeihypa qptdlrctfs cgiaeltpdl diksmakqad ealyrakhgg rnrievyrpd
      541 ar