MULTISPECIES: MFS transporter [Pseudomonas].

LOCUS       WP_003106206             388 aa            linear   BCT 28-JUL-2024
ACCESSION   WP_003106206
VERSION     WP_003106206.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 388)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 388)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13023516
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..388
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..388
                     /product="MFS transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=39405
     Region          5..341
                     /region_name="MFS_NepI_like"
                     /note="Purine ribonucleoside efflux pump NepI and similar
                     transporters of the Major Facilitator Superfamily;
                     cd17324"
                     /db_xref="CDD:340882"
     Site            order(15..16,19..20,23,55,105..106,108..110,113,133,
                     136..137,140,209,212..213,216..218,221,249,253,302..303,
                     307,311,325,328..329,332..333,336)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340882"
ORIGIN      
        1 mplivyvlga aifalttsey mvaglmpala aefgvsfaai gylvtfyaga mavggplltt
       61 allrvprkna llglialfvv gqvigalapg yavmvaarlv tavaaaaffg valtacaelv
      121 egnqfgrass lvlgglmvgt vlglpvatwl gewygwrasf favalvavlv gllvlqlmpa
      181 ipgsagsgsl reelkvfrna hlwwvyatsl lligatfagf tyfvpiltev sgfsastvpl
      241 llvvyglatl vgnnivgrla drhtiavlaf gllaaiaamv afalfgqvpa vavaalvvig
      301 ltgvsmnpal vtrgarvghn nmlvnsvhta cimlgvmags wigglgiagg fglqgalwvg
      361 aalgvlallt llpelrfara pvggalgr