MULTISPECIES: SDR family NAD(P)-dependent oxidoreductase

LOCUS       WP_003106196             304 aa            linear   BCT 02-MAR-2025
            [Pseudomonas].
ACCESSION   WP_003106196
VERSION     WP_003106196.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 304)
  AUTHORS   Yamashita,A., Kato,H., Wakatsuki,S., Tomizaki,T., Nakatsu,T.,
            Nakajima,K., Hashimoto,T., Yamada,Y. and Oda,J.
  TITLE     Structure of tropinone reductase-II complexed with NADP+ and
            pseudotropine at 1.9 A resolution: implication for stereospecific
            substrate binding and catalysis
  JOURNAL   Biochemistry 38 (24), 7630-7637 (1999)
   PUBMED   10387002
REFERENCE   2  (residues 1 to 304)
  AUTHORS   Benach,J., Atrian,S., Gonzalez-Duarte,R. and Ladenstein,R.
  TITLE     The refined crystal structure of Drosophila lebanonensis alcohol
            dehydrogenase at 1.9 A resolution
  JOURNAL   J Mol Biol 282 (2), 383-399 (1998)
   PUBMED   9735295
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF012334.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF00106.31
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..304
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..304
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /calculated_mol_wt=31901
     Region          15..268
                     /region_name="Rossmann-fold NAD(P)(+)-binding proteins"
                     /note="A large family of proteins that share a
                     Rossmann-fold NAD(P)H/NAD(P)(+) binding (NADB) domain. The
                     NADB domain is found in numerous dehydrogenases of
                     metabolic pathways such as glycolysis, and many other
                     redox enzymes. NAD binding involves numerous...; cl21454"
                     /db_xref="CDD:473865"
     Site            order(19,21..22,24,43..45,96..98,146..148,161,165,
                     191..194)
                     /site_type="other"
                     /note="NAD(P) binding site [chemical binding]"
                     /db_xref="CDD:187535"
     Site            order(120,148,161,165)
                     /site_type="active"
                     /db_xref="CDD:187535"
ORIGIN      
        1 mlftskplsp qgrhvlitga ssglgretal hlaeqgfqvi agvrrqedge rlanacpsgr
       61 istllidvtd eesigraaaq vaekvgdtgl wglvnnagic isaplecvss dllrrqlevn
      121 ligqlavtra ilpllrrgga arlvnvtsgl gsvaipylga ysaaqfakeg vsdalrrela
      181 pmgiqvsvvs pgaiwtpiwg kiasegeral adapdavadl yrdtylrflq anedgarnsa
      241 tkpadvaaav haaltaakpr tryrvgadvr rgtllarllp dsvidgmfrp ivtaapaake
      301 eqra