MULTISPECIES: two-component system response regulator cyclic

LOCUS       WP_003106013             392 aa            linear   BCT 20-NOV-2023
            di-GMP-specific phosphodiesterase RocR [Pseudomonas].
ACCESSION   WP_003106013
VERSION     WP_003106013.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 392)
  AUTHORS   Kotaka,M., Dutta,S., Lee,H.C., Lim,M.J., Wong,Y., Rao,F.,
            Mitchell,E.P., Liang,Z.X. and Lescar,J.
  TITLE     Expression, purification and preliminary crystallographic analysis
            of Pseudomonas aeruginosa RocR protein
  JOURNAL   Acta Crystallogr Sect F Struct Biol Cryst Commun 65 (Pt 10),
            1035-1038 (2009)
   PUBMED   19851016
REFERENCE   2  (residues 1 to 392)
  AUTHORS   Rao,F., Yang,Y., Qi,Y. and Liang,Z.X.
  TITLE     Catalytic mechanism of cyclic di-GMP-specific phosphodiesterase: a
            study of the EAL domain-containing RocR from Pseudomonas aeruginosa
  JOURNAL   J Bacteriol 190 (10), 3622-3631 (2008)
   PUBMED   18344366
REFERENCE   3  (residues 1 to 392)
  AUTHORS   Kulasekara,H.D., Ventre,I., Kulasekara,B.R., Lazdunski,A.,
            Filloux,A. and Lory,S.
  TITLE     A novel two-component system controls the expression of Pseudomonas
            aeruginosa fimbrial cup genes
  JOURNAL   Mol Microbiol 55 (2), 368-380 (2005)
   PUBMED   15659157
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR013455
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..392
                     /gene="rocR"
     Protein         1..392
                     /product="two-component system response regulator cyclic
                     di-GMP-specific phosphodiesterase RocR"
                     /calculated_mol_wt=42706
     Region          4..127
                     /region_name="REC_RocR"
                     /note="phosphoacceptor receiver (REC) domain of response
                     regulator RocR; cd17530"
                     /db_xref="CDD:381086"
     Site            order(11..13,15,17..18,24..25,33,39,58,60,85,87..90,92,
                     107..108,112,115..117,119..121,123..124,127)
                     /site_type="other"
                     /note="tetramer interface [polypeptide binding]"
                     /db_xref="CDD:381086"
     Region          145..384
                     /region_name="EAL"
                     /note="EAL domain. This domain is found in diverse
                     bacterial signaling proteins. It is called EAL after its
                     conserved residues and is also known as domain of unknown
                     function 2 (DUF2). The EAL domain has been shown to
                     stimulate degradation of a second...; cd01948"
                     /db_xref="CDD:238923"
ORIGIN      
        1 mndlnvlvle depfqrlvav talkkvvpgs ileaadgkea vailescghv diaicdlqms
       61 gmdglaflrh aslsgkvhsv ilssevdpil rqatismiec lglnflgdlg kpfslerita
      121 lltrynarrq dlprqievae lpsvadvvrg ldngefeayy qpkvaldggg ligaevlarw
      181 nhphlgvlpp shflyvmety nlvdklfwql fsqglatrrk laqlgqpinl afnvhpsqlg
      241 sralaenisa lltefhlpps svmfeitetg lisapassle nlvrlrimgc glamddfgag
      301 yssldrlcef pfsqikldrt fvqkmktqpr scavissvva laqalgislv vegvesdeqr
      361 vrlielgcsi aqgylfarpm peqhfldycs gs