MULTISPECIES: glucose-1-phosphate thymidylyltransferase RfbA

LOCUS       WP_003105518             293 aa            linear   BCT 09-DEC-2024
            [Pseudomonas].
ACCESSION   WP_003105518
VERSION     WP_003105518.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 293)
  AUTHORS   Ma,Y., Mills,J.A., Belisle,J.T., Vissa,V., Howell,M., Bowlin,K.,
            Scherman,M.S. and McNeil,M.
  TITLE     Determination of the pathway for rhamnose biosynthesis in
            mycobacteria: cloning, sequencing and expression of the
            Mycobacterium tuberculosis gene encoding
            alpha-D-glucose-1-phosphate thymidylyltransferase
  JOURNAL   Microbiology (Reading) 143 (Pt 3), 937-945 (1997)
   PUBMED   9084178
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR01207.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..293
                     /gene="rfbA"
     Protein         1..293
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /EC_number="2.7.7.24"
                     /GO_function="GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /calculated_mol_wt=32326
     Region          4..289
                     /region_name="rmlA"
                     /note="glucose-1-phosphate thymidylyltransferase, short
                     form; TIGR01207"
                     /db_xref="CDD:130274"
     Site            order(8,10..11,82,85..88,110,146,161..162,172,200)
                     /site_type="active"
                     /note="substrate binding site [active]"
                     /db_xref="CDD:133019"
     Site            order(14,17..19,22..23,27..29,31..34,37,62,114..115,
                     137..140,144..145,223..225,229..230,233,236..238,241..242)
                     /site_type="active"
                     /note="tetramer interface [active]"
                     /db_xref="CDD:133019"
ORIGIN      
        1 mkrkgiilag gsgtrlhpat laiskqllpv ydkpmiyypl stlmlagire iliistpqdt
       61 prfqqllgdg snwgldlqya vqpspdglaq afligesfig ndlsalvlgd nlyyghdfhe
      121 llgsasqrqt gasvfayhvl dperygvvef dqggkaisle ekplepksny avtglyfydq
      181 qvvdiardlk psprgeleit dvnraylerg qlsveimgrg yawldtgthd slleagqfia
      241 tlenrqglkv acpeeiayrq kwidaaqlek laaplakngy gqylkrllte tvy