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MULTISPECIES: LysR substrate-binding domain-containing protein


LOCUS       WP_003105226             308 aa            linear   BCT 26-FEB-2025
            [Pseudomonas].
ACCESSION   WP_003105226
VERSION     WP_003105226.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 308)
  AUTHORS   Tyrrell,R., Verschueren,K.H., Dodson,E.J., Murshudov,G.N., Addy,C.
            and Wilkinson,A.J.
  TITLE     The structure of the cofactor-binding fragment of the LysR family
            member, CysB: a familiar fold with a surprising subunit arrangement
  JOURNAL   Structure 5 (8), 1017-1032 (1997)
   PUBMED   9309218
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF015431.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF03466.25
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..308
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /calculated_mol_wt=33923
     Region          15..65
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          100..302
                     /region_name="PBP2_Pa0477"
                     /note="The C-terminal substrate biniding domain of an
                     uncharacterized LysR-like transcriptional regulator Pa0477
                     related to DntR, contains the type 2 periplasmic binding
                     fold; cd08468"
                     /db_xref="CDD:176157"
     Site            order(106,108..109,113,174,211,278)
                     /site_type="other"
                     /note="putative substrate binding pocket [chemical
                     binding]"
                     /db_xref="CDD:176157"
     Site            order(107,110..111,114..115,118..119,121..122,125..126,
                     128..132,134,200,228..232,235..236,239..240,243,257)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:176157"
ORIGIN      
        1 mhpllrrldl nlllvfdaly rhrnvgtaas elaisasafs halgrlrqgl ddelflrqgn
       61 rmqptqraeh laaavaaalr algegleewr pfvpgqsqrt fvfaatdyta fallpplmnr
      121 lqhsapgvrl rlvnaerkls vealasgrid falgydeehe rlpegiqahd wfadryvvva
      181 rrdhprlaga ptlegylaer havvtpwned sgvidrllar sglrrevavq lptvlaalfl
      241 agstdfllta prhaaralae aaglalypap fdippyvlrl yshvqhvgrd ahawmigqlk
      301 gldisrtg