MULTISPECIES: MFS transporter [Pseudomonas].

LOCUS       WP_003103910             462 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_003103910
VERSION     WP_003103910.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 462)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 462)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 462)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13024624
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..462
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=48687
     Region          20..393
                     /region_name="MFS_YajR_like"
                     /note="Escherichia coli inner membrane transport protein
                     YajR and similar multidrug-efflux transporters of the
                     Major Facilitator Superfamily; cd17472"
                     /db_xref="CDD:341025"
     Site            order(27..28,31..32,35,68,118..119,121..123,126,148,
                     151..152,155,224,227..228,231..233,236,264,268,312..313,
                     317,321,344,347..348,351..352,355)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:341025"
ORIGIN      
        1 mhdshterms gtetraavgl slvfafrmlg mfmvlpvlat ygqdlagatp aliglaigay
       61 gltqailqip fgtisdrigr rpvivvglli faagaalaan adsiwgviag rvlqgagais
      121 aavmallsdl treqhrtkam amigmsigvs favamvlgpv lthlfglhgl fwftagmalv
      181 glllilffvp qpdhmtqhre ssvarqallp tlkhgdllrl dagililhai lmasfvalpl
      241 alvhegglpk eqhwwvylta llvgffgmvp fiiyaekkrr mkrvltgava tllacelffl
      301 vfghslamlv vgtvvfftaf nlleaslpsl vskvspaggk gtamgvysts qflgaalggi
      361 lggwmfqhgg lsmvfigcav laalwlaiav tmreppyvts irlplapaal qdavlvqrfr
      421 alpgvadavv vaeeaaayvk vdtqqvdrta lerlaqaapg gc