MULTISPECIES: mechanosensitive ion channel family protein

LOCUS       WP_003103754             442 aa            linear   BCT 01-JAN-2025
            [Pseudomonas].
ACCESSION   WP_003103754
VERSION     WP_003103754.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 442)
  AUTHORS   Malcolm,H.R. and Maurer,J.A.
  TITLE     The mechanosensitive channel of small conductance (MscS)
            superfamily: not just mechanosensitive channels anymore
  JOURNAL   Chembiochem 13 (14), 2037-2043 (2012)
   PUBMED   22915507
REFERENCE   2  (residues 1 to 442)
  AUTHORS   Haswell,E.S., Phillips,R. and Rees,D.C.
  TITLE     Mechanosensitive channels: what can they do and how do they do it?
  JOURNAL   Structure 19 (10), 1356-1369 (2011)
   PUBMED   22000509
REFERENCE   3  (residues 1 to 442)
  AUTHORS   Pivetti,C.D., Yen,M.R., Miller,S., Busch,W., Tseng,Y.H., Booth,I.R.
            and Saier,M.H. Jr.
  TITLE     Two families of mechanosensitive channel proteins
  JOURNAL   Microbiol Mol Biol Rev 67 (1), 66-85 (2003)
   PUBMED   12626684
REFERENCE   4  (residues 1 to 442)
  AUTHORS   Martinac,B.
  TITLE     Mechanosensitive channels in prokaryotes
  JOURNAL   Cell Physiol Biochem 11 (2), 61-76 (2001)
   PUBMED   11275684
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11430441
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..442
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..442
                     /product="mechanosensitive ion channel family protein"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=49264
     Region          <177..399
                     /region_name="MscS"
                     /note="Small-conductance mechanosensitive channel [Cell
                     wall/membrane/envelope biogenesis]; COG0668"
                     /db_xref="CDD:440432"
ORIGIN      
        1 mdstslldql sgywsaldqh pilhaglafg lllvgalilg rvaryivlya anllarqpal
       61 hwlgdlirnk vfqrlaqttp sllvqfglpw ipempdkaah flgnlalaft vlflilalta
      121 llnalldiya rtehartrsi kgyvqlakia vfvfgaiiiv siiidrspll llsglgamsa
      181 vlllvykdtl msfvasvqlt sndmlrvgdw iempqvgadg dvvditlytv kvqnfdktiv
      241 svptwrlmse sfknwrgmqq sggrrikrai yvdssqvrfl dekeerrlsq vrllteymar
      301 kqtelqewna anggvaplaa nrrrltnigt frayalaylq nhpdihphmt cmvrqlqpta
      361 qgipleiycf trttawvdye riqgdvfdyl lavmpefglg ayqqpsgqdl rqglqgmleg
      421 rdaearsfea laapsrsdea tv