MULTISPECIES: 1-deoxy-D-xylulose-5-phosphate synthase

LOCUS       WP_003102816             627 aa            linear   BCT 20-NOV-2023
            [Pseudomonas].
ACCESSION   WP_003102816
VERSION     WP_003102816.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 627)
  AUTHORS   Lois,L.M., Campos,N., Putra,S.R., Danielsen,K., Rohmer,M. and
            Boronat,A.
  TITLE     Cloning and characterization of a gene from Escherichia coli
            encoding a transketolase-like enzyme that catalyzes the synthesis
            of D-1-deoxyxylulose 5-phosphate, a common precursor for
            isoprenoid, thiamin, and pyridoxol biosynthesis
  JOURNAL   Proc Natl Acad Sci U S A 95 (5), 2105-2110 (1998)
   PUBMED   9482846
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00204.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..627
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..627
                     /gene="dxs"
     Protein         1..627
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=67919
     Region          15..624
                     /region_name="Dxs"
                     /note="Deoxyxylulose-5-phosphate synthase [Coenzyme
                     transport and metabolism, Lipid transport and metabolism];
                     COG1154"
                     /db_xref="CDD:440768"
ORIGIN      
        1 mpktlheipr erpatplldr asspaelrrl geadletlad elrqyllytv gqtgghfgag
       61 lgvveltial hyvfdtpddr lvwdvghqay phkilterre lmgtlrqkng laafprraes
      121 eydtfgvghs stsisaalgm aiaarlqgke rksvavigdg altagmafea lnhasevdad
      181 mlvilndndm sishnvggls nylakilssr tyssmregsk kvlsrlpgaw eiarrteeya
      241 kgmlvpgtlf eelgwnyigp idghdlptlv atlrnmrdmk gpqflhvvtk kgkgfapael
      301 dpigyhaitk leapgsapkk tggpkyssvf gqwlcdmaaq darllgitpa mkegsdlvaf
      361 seryperyfd vaiaeqhavt laagmacegm kpvvaiystf lqraydqlih dvavqhldvl
      421 faidraglvg edgpthagsf disylrcipg mlvmtpsded elrkllttgy lfdgpaavry
      481 prgsgpnhpi dpdlqpveig kgvvrrrggr vallvfgvql aeamkvaesl datvvdmrfv
      541 kpldealvre lagshellvt ieenavmgga gsavgeflas eglevpllql glpdyyveha
      601 kpsemlaecg ldaagiekav rqrldrq