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MULTISPECIES: 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD


LOCUS       WP_003102417             450 aa            linear   BCT 20-NOV-2023
            [Pseudomonas].
ACCESSION   WP_003102417
VERSION     WP_003102417.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 450)
  AUTHORS   Hur,S., Stroud,R.M. and Finer-Moore,J.
  TITLE     Substrate recognition by RNA 5-methyluridine methyltransferases and
            pseudouridine synthases: a structural perspective
  JOURNAL   J. Biol. Chem. 281 (51), 38969-38973 (2006)
   PUBMED   17085441
REFERENCE   2  (residues 1 to 450)
  AUTHORS   Lee,T.T., Agarwalla,S. and Stroud,R.M.
  TITLE     A unique RNA Fold in the RumA-RNA-cofactor ternary complex
            contributes to substrate selectivity and enzymatic function
  JOURNAL   Cell 120 (5), 599-611 (2005)
   PUBMED   15766524
REFERENCE   3  (residues 1 to 450)
  AUTHORS   Agarwalla,S., Stroud,R.M. and Gaffney,B.J.
  TITLE     Redox reactions of the iron-sulfur cluster in a ribosomal RNA
            methyltransferase, RumA: optical and EPR studies
  JOURNAL   J. Biol. Chem. 279 (33), 34123-34129 (2004)
   PUBMED   15181002
REFERENCE   4  (residues 1 to 450)
  AUTHORS   Lee,T.T., Agarwalla,S. and Stroud,R.M.
  TITLE     Crystal structure of RumA, an iron-sulfur cluster containing E.
            coli ribosomal RNA 5-methyluridine methyltransferase
  JOURNAL   Structure 12 (3), 397-407 (2004)
   PUBMED   15016356
REFERENCE   5  (residues 1 to 450)
  AUTHORS   Madsen,C.T., Mengel-Jorgensen,J., Kirpekar,F. and Douthwaite,S.
  TITLE     Identifying the methyltransferases for m(5)U747 and m(5)U1939 in
            23S rRNA using MALDI mass spectrometry
  JOURNAL   Nucleic Acids Res. 31 (16), 4738-4746 (2003)
   PUBMED   12907714
REFERENCE   6  (residues 1 to 450)
  AUTHORS   Agarwalla,S., Kealey,J.T., Santi,D.V. and Stroud,R.M.
  TITLE     Characterization of the 23 S ribosomal RNA m5U1939
            methyltransferase from Escherichia coli
  JOURNAL   J. Biol. Chem. 277 (11), 8835-8840 (2002)
   PUBMED   11779873
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF009639.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK13168
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     gene            1..450
                     /gene="rlmD"
     Protein         1..450
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /EC_number="2.1.1.190"
                     /GO_function="GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006396 - RNA processing [Evidence IEA]"
                     /calculated_mol_wt=48940
     Region          7..450
                     /region_name="rumA"
                     /note="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD; PRK13168"
                     /db_xref="CDD:237291"
ORIGIN      
        1 marnkgglrf qpsggargpa ipvgkkqrlt ierlahdgrg iaheagmtwf vsgglpgeel
       61 earvlgarsk vvdarserlf sssdlrrrep ctvagrcggc tlqhlehgeq lalkqrtlqe
      121 qlqrfagiep eewaaplvgp efgyrrrari avrwdararr ldvgfrasas qeivafdecl
      181 vlvpplqtia ralpallqdf rkpesighve lfhgtasall lrhttalvde drqrlaafcs
      241 ahqaqlwlqg aeqplpvepa aelgyslgdw qltlayrpgd fvqvnapvne smirqaldwl
      301 aptadervld lfcglgnfsl plarrvarvv gvegvaamve raganalang lgnahffqad
      361 lskalaeapw aeqgftavll dpprdgafea vremsslgar rvvyvscnpa tlardagema
      421 rqgyrlkrag ildmfpqtah veamalfeag