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MULTISPECIES: glycine cleavage system protein H [Pseudomonas].


LOCUS       WP_003102267             155 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_003102267
VERSION     WP_003102267.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 155)
  AUTHORS   Okamura-Ikeda,K., Hosaka,H., Maita,N., Fujiwara,K., Yoshizawa,A.C.,
            Nakagawa,A. and Taniguchi,H.
  TITLE     Crystal structure of aminomethyltransferase in complex with
            dihydrolipoyl-H-protein of the glycine cleavage system:
            implications for recognition of lipoyl protein substrate,
            disease-related mutations, and reaction mechanism
  JOURNAL   J Biol Chem 285 (24), 18684-18692 (2010)
   PUBMED   20375021
REFERENCE   2  (residues 1 to 155)
  AUTHORS   Kikuchi,G., Motokawa,Y., Yoshida,T. and Hiraga,K.
  TITLE     Glycine cleavage system: reaction mechanism, physiological
            significance, and hyperglycinemia
  JOURNAL   Proc Jpn Acad Ser B Phys Biol Sci 84 (7), 246-263 (2008)
   PUBMED   18941301
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10785558
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..155
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..155
                     /product="glycine cleavage system protein H"
                     /EC_number="1.4.1.27"
                     /GO_component="GO:0005960 - glycine cleavage complex
                     [Evidence IEA]"
                     /GO_process="GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /GO_process="GO:0019464 - glycine decarboxylation via
                     glycine cleavage system [Evidence IEA]"
                     /calculated_mol_wt=16998
     Region          9..137
                     /region_name="GcvH"
                     /note="Glycine cleavage system protein H (lipoate-binding)
                     [Amino acid transport and metabolism]; COG0509"
                     /db_xref="CDD:440275"
ORIGIN      
        1 msanlhglef pdglfyapdy nlwlreevdg sltlglsayg calygeifaf tpkrdgwhie
       61 rdrsfgvvef akaassarsp lagtllasnp avvkrpalin rdcygegwmv rlqpddwasa
      121 rsaflqgdaa reafaermrl dgfdpqhpgv qaldf