MULTISPECIES: Fic/DOC family protein [Gammaproteobacteria].

LOCUS       WP_003102000             256 aa            linear   BCT 19-FEB-2025
ACCESSION   WP_003102000
VERSION     WP_003102000.1
KEYWORDS    RefSeq.
SOURCE      Gammaproteobacteria
  ORGANISM  Gammaproteobacteria
            Bacteria; Pseudomonadati; Pseudomonadota.
REFERENCE   1  (residues 1 to 256)
  AUTHORS   Veyron,S., Oliva,G., Rolando,M., Buchrieser,C., Peyroche,G. and
            Cherfils,J.
  TITLE     A Ca2+-regulated deAMPylation switch in human and bacterial FIC
            proteins
  JOURNAL   Nat Commun 10 (1), 1142 (2019)
   PUBMED   30850593
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 256)
  AUTHORS   Engel,P., Goepfert,A., Stanger,F.V., Harms,A., Schmidt,A.,
            Schirmer,T. and Dehio,C.
  TITLE     Adenylylation control by intra- or intermolecular active-site
            obstruction in Fic proteins
  JOURNAL   Nature 482 (7383), 107-110 (2012)
   PUBMED   22266942
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 256)
  AUTHORS   Kinch,L.N., Yarbrough,M.L., Orth,K. and Grishin,N.V.
  TITLE     Fido, a novel AMPylation domain common to fic, doc, and AvrB
  JOURNAL   PLoS One 4 (6), e5818 (2009)
   PUBMED   19503829
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11450684
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..256
                     /organism="Gammaproteobacteria"
                     /db_xref="taxon:1236"
     Protein         1..256
                     /product="Fic/DOC family protein"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0070733 - AMPylase activity [Evidence
                     IEA]"
                     /GO_process="GO:0018117 - protein adenylylation [Evidence
                     IEA]"
                     /calculated_mol_wt=29135
     Region          1..198
                     /region_name="FIDO"
                     /note="Fido, protein-threonine AMPylation domain [Signal
                     transduction mechanisms]; COG2184"
                     /db_xref="CDD:441787"
ORIGIN      
        1 msfdpfgdfe ttgylrnslg lkdpaevken ehfsfemgld ealsylertk nlnyqallqv
       61 hrllfekfyp wagrdrlelv phlsvwkgpk gaprrtffes pamieravdy alslaskkqg
      121 fmqkpgevmg llcfahpfld gngrsillfy melsyragfa idwastrkdd ylqalddeih
      181 npgkghldry lvpfvvpihs rdqwpeiigq ingldgmdge nityenlddp evqkvyaayh
      241 aehpypakdg tpdsep