MULTISPECIES: MFS transporter [Pseudomonas].

LOCUS       WP_003101861             441 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_003101861
VERSION     WP_003101861.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 441)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 441)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 441)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13022908
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..441
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..441
                     /product="MFS transporter"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=48574
     Region          33..434
                     /region_name="MFS_ExuT_GudP_like"
                     /note="Hexuronate transporter, Glucarate transporter, and
                     similar transporters of the Major Facilitator Superfamily;
                     cd17319"
                     /db_xref="CDD:340877"
     Site            order(47..48,51..52,55,87,137..138,140..142,145,165,
                     168..169,172,256,259..260,263..265,268,298,302,359..360,
                     364,368,384,387..388,391..392,395)
                     /site_type="other"
                     /note="putative chemical substrate binding pocket
                     [chemical binding]"
                     /db_xref="CDD:340877"
ORIGIN      
        1 mihssssrll aadapresrg grirnafavg rtrwgmlalv ffattlnyid raalgvmqpi
       61 laekmswtam dyaninfwfq vgyaigfilq grfidkvgvk rafflavllw slatgahgla
      121 tsaagfmvcr filglteaan ypacvkttrl wfpagerava tgifnagtnv gamvtpallp
      181 lilgvwgwqa aflcmsalgl vwlvfwwrny ynpeehprvk qseleyiqqq eeppatrvpf
      241 sqilrrrgtw afalaysita pvfwfylywl ppflnqqygl gisvtqmgip liliwltadf
      301 gsvgggilss wligrgmpai rarllsmllf activgvvfa anasglwiav laialavgah
      361 qawtaniwsl vmdytpkhlm stvfgfggmc aalggmfmtq ivggvltatn nnyavlftmi
      421 pamyfialtw lyfmaprrie a