MULTISPECIES: HAL/PAL/TAL family ammonia-lyase [Pseudomonas].

LOCUS       WP_003101754             510 aa            linear   BCT 20-JAN-2025
ACCESSION   WP_003101754
VERSION     WP_003101754.1
KEYWORDS    RefSeq.
SOURCE      Pseudomonas
  ORGANISM  Pseudomonas
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Pseudomonadales; Pseudomonadaceae.
REFERENCE   1  (residues 1 to 510)
  AUTHORS   Turner,N.J.
  TITLE     Ammonia lyases and aminomutases as biocatalysts for the synthesis
            of alpha-amino and beta-amino acids
  JOURNAL   Curr Opin Chem Biol 15 (2), 234-240 (2011)
   PUBMED   21131229
REFERENCE   2  (residues 1 to 510)
  AUTHORS   Louie,G.V., Bowman,M.E., Moffitt,M.C., Baiga,T.J., Moore,B.S. and
            Noel,J.P.
  TITLE     Structural determinants and modulation of substrate specificity in
            phenylalanine-tyrosine ammonia-lyases
  JOURNAL   Chem Biol 13 (12), 1327-1338 (2006)
   PUBMED   17185228
REFERENCE   3  (residues 1 to 510)
  AUTHORS   Baedeker,M. and Schulz,G.E.
  TITLE     Autocatalytic peptide cyclization during chain folding of histidine
            ammonia-lyase
  JOURNAL   Structure 10 (1), 61-67 (2002)
   PUBMED   11796111
REFERENCE   4  (residues 1 to 510)
  AUTHORS   Schwede,T.F., Retey,J. and Schulz,G.E.
  TITLE     Crystal structure of histidine ammonia-lyase revealing a novel
            polypeptide modification as the catalytic electrophile
  JOURNAL   Biochemistry 38 (17), 5355-5361 (1999)
   PUBMED   10220322
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10006831
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..510
                     /organism="Pseudomonas"
                     /db_xref="taxon:286"
     Protein         1..510
                     /product="HAL/PAL/TAL family ammonia-lyase"
                     /EC_number="4.3.1.-"
                     /GO_function="GO:0016841 - ammonia-lyase activity
                     [Evidence IEA]"
                     /GO_process="GO:0170035 - L-amino acid catabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=53325
     Region          5..502
                     /region_name="HutH"
                     /note="Histidine ammonia-lyase [Amino acid transport and
                     metabolism]; COG2986"
                     /db_xref="CDD:442225"
ORIGIN      
        1 msdlpsvvfg dgplrwqelv avarhgarle lsaaawarid naraivcriv angeraygis
       61 tglgalcdvl legeqlaels rntllshacg vgeplrdeqt raiicaavan ysqgksgldr
      121 slvegllall nhgitpqvpa qgsvgylthm ahvgiallgi gevsyrgsvv paaaalaaeg
      181 latvrlgakd glclvngtpc mtglaclald daqrlaqwad vigamsfeal rgqlaafdae
      241 ivalkphpgm qrvaanlral lagsqvlena rgirtqdals irsipqihga crdqlahaar
      301 qietelnsat dnplllgtpe ayrvvsqanp hgesvamaad llaiavaelg gvaerrldrl
      361 vnplvsglpa flvgkpgvns gmmitqyvaa slagenrqla qpavvdnfvt salqedhlsl
      421 gtsaalklgr alenlrrila ieyllaaqaf eflapqrfgq gtaaawgilr ervpaydtdr
      481 wlapdiasaa ailgerksla rlaasigdlq