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LOCUS WP_003101374 442 aa linear BCT 01-JAN-2025 ACCESSION WP_003101374 VERSION WP_003101374.1 KEYWORDS RefSeq. SOURCE Pseudomonadota ORGANISM Pseudomonadota Bacteria; Pseudomonadati. REFERENCE 1 (residues 1 to 442) AUTHORS Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P. TITLE Understanding transport by the major facilitator superfamily (MFS): structures pave the way JOURNAL Nat Rev Mol Cell Biol 17 (2), 123-132 (2016) PUBMED 26758938 REFERENCE 2 (residues 1 to 442) AUTHORS Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D. TITLE Energy coupling mechanisms of MFS transporters JOURNAL Protein Sci 24 (10), 1560-1579 (2015) PUBMED 26234418 REFERENCE 3 (residues 1 to 442) AUTHORS Yan,N. TITLE Structural Biology of the Major Facilitator Superfamily Transporters JOURNAL Annu Rev Biophys 44, 257-283 (2015) PUBMED 26098515 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 13022776 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..442 /organism="Pseudomonadota" /db_xref="taxon:1224" Protein 1..442 /product="MFS transporter" /GO_component="GO:0016020 - membrane [Evidence IEA]" /GO_function="GO:0022857 - transmembrane transporter activity [Evidence IEA]" /GO_process="GO:0055085 - transmembrane transport [Evidence IEA]" /calculated_mol_wt=47465 Region 21..409 /region_name="MFS_SV2_like" /note="Metazoan Synaptic vesicle glycoprotein 2 (SV2) and related small molecule transporters of the Major Facilitator Superfamily; cd17316" /db_xref="CDD:340874" Site order(31..32,35..36,39,71,121..122,124..126,129,149, 152..153,156,259,262..263,266..268,271,298,302,353..354, 358,362,378,381..382,385..386,389) /site_type="other" /note="putative chemical substrate binding pocket [chemical binding]" /db_xref="CDD:340874" ORIGIN 1 mtnpttsied vplnafhrll tlrsgggsfv dgyvlsiigv amlqmtaalq lssfwqgmia 61 asalvgiffg gflggwltdr lgrrrlffvg pslfvlasla qygvdsaaal fvlrfligva 121 vgieypvata llveflpkky rgprlatlti lwfagaafay lvgdlilrsg gedawrlvla 181 staaigavlf llrigtpesp rwllskgrda daervirqvy geafslenlp eqalerkvti 241 whllyagygk rmlfvtlfwt csvipvfavy afapkvllal nlkgdwasyg svaitllfvi 301 gciiatrlin rigrrcmllh sflwsglall glgvfhagse atilglfgay alfiggaqvl 361 qlvypnelfp teirafavgv gtslsrvgaa vgtylvplsl etlgtaqtmy aaalvtllgl 421 lvtwalapet rslnlqqaas lt